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Lymphatic malformation
MONDO:0019313Primary lymphedema is caused by anatomic or functional defects in the lymphatic system, resulting in chronic swelling of body parts and lymphatic-system malformation.
Also known as: hereditary lymphedema, lymphedema, hereditary
55 clinical trials for this condition and its sub-types, 17 tagged with Lymphatic malformation itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Lymphatic malformation
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Noonan syndrome 21 trials · 24 incl. sub-types
14 sub-types
- Noonan syndrome 3 2 trials
- Noonan syndrome 5 1 trial
- Noonan syndrome 1 0 trials
- Noonan syndrome 10 0 trials
- Noonan syndrome 11 0 trials
- Noonan syndrome 13 0 trials
- Noonan syndrome 14 0 trials
- Noonan syndrome 2 0 trials
- Noonan syndrome 4 0 trials
- Noonan syndrome 6 0 trials
- Noonan syndrome 7 0 trials
- Noonan syndrome 8 0 trials
- Noonan syndrome 9 0 trials
- Noonan syndrome 12 0 trials
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Lymphatic malformation 5 8 trials
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Lymphatic malformation 12 2 trials
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Dahlberg-Borer-Newcomer syndrome 0 trials
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Hennekam syndrome 0 trials
3 sub-types
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Norman-Roberts syndrome 0 trials
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Campomelia, Cumming type 0 trials
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Lymphatic malformation 1 0 trials
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Lymphatic malformation 10 0 trials
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Lymphatic malformation 11 0 trials
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Lymphatic malformation 13 0 trials
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Lymphatic malformation 14 0 trials
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Lymphatic malformation 2 0 trials
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Lymphatic malformation 3 0 trials
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Lymphatic malformation 4 0 trials
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Lymphatic malformation 6 0 trials
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Lymphatic malformation 7 0 trials
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Lymphatic malformation 8 0 trials
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Lymphatic malformation 9 0 trials
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Lymphedema-distichiasis syndrome 0 trials
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Yellow nail syndrome 0 trials
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Cancer drug tested against deadly infant heart disease
Disease control Not yet recruitingResearchers are testing whether trametinib, an FDA-approved cancer drug, can help infants with RASopathies who have a severe, life-threatening heart condition called hypertrophic cardiomyopathy. The trial enrolls about 25 babies with a confirmed genetic diagnosis. Participants re…
Phase 3 • Sponsor: Carelon Research • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Which injection works best for Children's lymphatic malformations? new trial aims to find out
Disease control Not yet recruitingThis study compares two injected drugs, bleomycin and doxycycline, to treat lymphatic malformations (abnormal fluid-filled sacs) in children under 12. About 92 kids will be randomly assigned to one treatment, and doctors will measure how much the malformation shrinks over six mon…
Phase 2 • Sponsor: Basharat Hussain • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New device aims to ease leg swelling in lymphedema patients
Symptom relief Not yet recruitingThis study tests if a new dynamic compression device, used with compression stockings, works as well as current treatments for reducing leg swelling in people with lymphedema. About 98 adults with stage II or III lymphedema will use either the new device or standard wraps and pum…
Sponsor: Jean-Paul Belgrado • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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New compression device could ease lymphedema swelling faster
Symptom relief Not yet recruitingThis study compares a new dynamic compression device to traditional bandages for reducing leg swelling in people with lymphedema. Over 5 days of intensive treatment, 110 participants will wear either the device or standard bandages. The goal is to see which method reduces excess …
Sponsor: Jean-Paul Belgrado • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New study aims to predict bleeding dangers in noonan syndrome patients
Knowledge-focused Not yet recruitingThis study looks at why people with Noonan syndrome often bleed easily, especially from the skin, mouth, or nose. Researchers will compare a simple questionnaire about bleeding history with blood tests in 100 patients. The goal is to find better ways to predict serious bleeding, …
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC