Legg-Calve-Perthes disease
MONDO:0007885A hip region disease that is characterized by uni- or bilateral avascular necrosis (AVN) of the femoral head in children. In a small percentage of cases, mutations in the COL2A1 gene were found to be responsible.
Also known as: Legg Calvé Perthes Disease, Legg-CALVE-Perthes disease, Legg-Calve-Perthes disease, Legg-Calve-Perthes symptom, Legg-Calve-Perthes syndrome, Legg-Calvé-Perthes disease, Legg-Perthes disease, Osteochondrosis of the capital femoral epiphysis
10 clinical trials for this condition and its sub-types, 9 tagged with Legg-Calve-Perthes disease itself.
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New hip implant aims to fix cartilage without replacement
Disease control OngoingThis early study is testing a new device called the ReNew Hip Implant in 15 people aged 14 to 64 with hip cartilage damage from conditions like osteoarthritis or hip impingement. The implant is surgically placed to repair the cartilage. Researchers are checking if it is safe and …
Sponsor: Cytex Therapeutics, Inc. • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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New drug aims to stop hip bone death from steroids
Disease control OngoingThis study tests a new drug called RAB001 in people with early-stage hip bone damage caused by long-term steroid use. About 160 participants will receive either a low, medium, or high dose of RAB001, or a standard bone drug (alendronate). The goal is to see if RAB001 can reduce t…
Phase 2 • Sponsor: ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New combo nerve block may ease hip surgery pain better
Symptom relief By invitation onlyThis study tests if adding two extra nerve blocks to a standard one can improve pain control and recovery after hip replacement surgery. About 60 adults having hip surgery will be randomly assigned to receive either the standard block alone or the standard block plus the extra bl…
Sponsor: Ataturk University • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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500 patients revisited: how do childhood hip surgeries hold up decades later?
Knowledge-focused OngoingThis study looks at how well treatments for childhood hip conditions (like hip dysplasia and Perthes disease) work over the long term. Researchers at Mayo Clinic are following 500 adults who were treated for these conditions as children. They will check how many needed another su…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC