Large artery stroke

This study tests whether adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency stroke treatment helps people recover better after a severe stroke caused by a large blood clot in the front part of the brain. About 692 adults who are el…

This study looks at whether a procedure called endovascular treatment (EVT) can help people who have had a mild stroke caused by a blocked large artery in the brain. About 300 participants will either receive EVT plus standard medical care or standard care alone. The goal is to s…

This was a very early (Phase 1) study that planned to give a mixture of cold saline, minocycline, and magnesium directly into the brain's arteries right after a stroke procedure to reopen blocked vessels. The goal was to see if this cocktail could safely protect brain tissue and …

This study looked at 800 adults who had a stroke from a large blood clot in the brain. It compared a new device called the NeVa Stent Retriever to standard devices used to remove the clot. The goal was to see if the new device could restore blood flow better and with fewer side e…

This study looks at whether tiny RNA particles called exosomal microRNAs in the blood can act as a 'stroke clock' for people with a severe type of stroke caused by a blocked large artery in the front of the brain. Researchers will compare blood samples from stroke patients to hea…

This study looks at whether a coordinated emergency system, like those used for trauma, can help more severe stroke patients get a clot removal procedure called mechanical thrombectomy. Researchers will compare data from before and after the system is put in place across Alabama.…

This study looks at tandem stroke, a severe type of stroke caused by two blockages in series (one in a neck artery and one in a brain artery). Researchers will analyze data from about 2880 patients treated between 2018 and 2024 to identify risk factors and compare outcomes of dif…