Keratoconus

This study tests whether a tiny steroid-releasing implant (Dextenza) placed in the tear duct works as well as standard steroid eye drops after corneal crosslinking surgery for keratoconus. About 20 people aged 13 and older with progressive keratoconus will receive either the impl…

This case report tests whether implanting a fresh corneal lenticule from a myopic donor, along with autologous serum drops, can safely thicken the cornea and improve vision in a person with advanced keratoconus. The procedure uses a femtosecond laser to place the graft. The goal …

This trial tests whether a corneal lenticule — a thin disc of tissue taken from a donor eye during a type of laser surgery — can be implanted into the cornea of people with progressive keratoconus, a condition where the cornea thins and bulges outward. The goal is to increase cor…

This registry collects long-term data from hundreds of people in Germany who have undergone corneal cross linking for keratoconus, a condition where the cornea thins and bulges, causing vision loss. The procedure uses riboflavin (vitamin B2) eye drops and UV light to stiffen the …

This phase 3 trial tests a procedure called corneal collagen crosslinking for people with progressive keratoconus, a condition where the cornea thins and bulges, blurring vision. The treatment uses riboflavin (vitamin B2) drops and UV light to stiffen the cornea. The study aims t…

This study tests whether a new surgical guide (the Alfonso nomogram) helps doctors place corneal ring implants more effectively in people with moderate keratoconus. Twenty-five adults aged 18–35 with progressive disease received the implant. Researchers will measure changes in vi…

This early study tests whether TN-001 eye drops are safe and can stop keratoconus, a disease that thins and bulges the cornea, from getting worse. About 20 adults with progressive keratoconus will use the drops twice daily for 3-6 weeks. Researchers will monitor for side effects …

This study compares a new AI system, called AEYE, against a human eye doctor in diagnosing keratoconus and deciding who is eligible for laser vision correction. The AI analyzes patient history, eye scans, and other data to make its recommendations. Researchers will check if the A…

This study looks at how keratoconus, a disease that thins and bulges the cornea, affects electrical signals in the eye and brain. Researchers will measure these signals in 50 adults with different stages of keratoconus using standard eye tests. The goal is to see if these measure…

This study uses a special light-based technique called Brillouin microscopy to measure the stiffness of the cornea in people with keratoconus, a condition where the cornea thins and bulges. Researchers will compare measurements before and after treatments like corneal cross-linki…