Keloid

This study tests whether the drug ritlecitinib can prevent keloids from returning after surgical removal. Keloids are raised, often itchy scars that grow beyond the original wound. The trial will enroll 30 adults who will take a daily pill for 36 weeks. Researchers will measure k…

This pilot study is testing whether radiation therapy can safely treat keloids (raised scars) when surgery isn't an option or has been refused. Fifteen adults with keloids will receive radiation over several sessions. Researchers will track side effects and measure if the keloids…

This study is testing whether a special PET-CT scan using a radioactive tracer called 68Ga-RGD can help doctors diagnose keloids and see how well treatment is working. Keloids are raised scars that grow beyond the original wound, and current diagnosis relies on physical exams. Th…

This study tests if applying a brief cold spray to keloid or hypertrophic scars right before a steroid injection can reduce pain and make the injection easier. About 30 adults will have each scar split into two halves: one half gets cold therapy plus the injection, the other gets…

This study tests a new drug called 9MW3811 for people with thick, raised scars that haven't improved in 6 months. About 30 adults will receive either the drug or a placebo to see if it makes scars look and feel better. The goal is to reduce scar thickness, color, pain, and itchin…

This study tests whether adding cryotherapy (freezing) to a standard injection treatment (5FU) works better for keloid scars than the injection alone. About 88 adults with painful or itchy keloids will receive either 5FU injections every 3 weeks or freezing followed by the same i…

This study tests a scar gel against a leading product to see which better prevents raised scars and improves scar appearance, hydration, and color. Eighty adults with recent scars (from C-sections, breast implants, or cuts) will use the gel daily for 90 days. Doctors and particip…

This study looks at keloid scars—raised, overgrown scars that can be itchy or painful—to understand why they form. Researchers will compare keloid tissue with normal skin from the same person, using lab tests to spot key molecules that drive scar growth. The goal is to uncover ne…

This study aims to find the genes that cause or contribute to keloid scarring. Researchers will analyze DNA from 7,000 people who have keloids, as well as their unaffected family members. The goal is to better understand why some people develop these raised scars, which could lea…