7,000 volunteers needed to crack the genetic code of keloids.
NCT ID NCT01619553
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to find the genes that cause or contribute to keloid scarring. Researchers will analyze DNA from 7,000 people who have keloids, as well as their unaffected family members. The goal is to better understand why some people develop these raised scars, which could lead to future treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could point toward genetic targets for future treatments or prevention of keloid scarring.
- What could go wrong
- This is an observational genetic study, not a treatment trial. It may not directly lead to new therapies, and results may take years to translate into clinical use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 7,000 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Apr 2009
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Individuals with diagnosed keloids.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * keloids; * unaffected individuals only if part of a participating keloid family Exclusion Criteria: * no keloids; * unaffected individuals only as part of a participating keloid family
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Connecticut Health Center (UCHC)
RECRUITINGFarmington, Connecticut, 06030-3705, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Sound waves and herbs take on 'Non-Killing Cancer' of keloid scars
- Do future doctors know the skin risks of tattoos and piercings?
- New PET scan tracer could spot keloids without a biopsy
- Can a simple ointment before surgery lead to better scars?
- Plasma zaps scars: new device aims to smooth skin