Invasive non-typhoidal salmonellosis
MONDO:0017944Invasive non-typhoidal salmonellosis (iNTS) is a rare bacterial infectious disease caused by extraintestinal infection of non-typhoidal serotypes of Salmonella enterica in patients with underlying HIV infection, malaria or malignancy. It has a high mortality rate and patients typically present with fever, pallor and respiratory signs (cough, tachnypnea, pneumonia). Gastrointestinal manifestations (diarrhea, vomit, abdominal pain) are not common. Occasionally, organ absseses, septic shock and meningitis may be observed.
Also known as: iNTS disease, invasive non-typhoidal salmonella disease
5 clinical trials for this condition and its sub-types, 5 tagged with Invasive non-typhoidal salmonellosis itself.
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New vaccine aims to protect african children from deadly salmonella
Vaccine CompletedThis study tests a new vaccine (iNTS-GMMA) designed to prevent severe Salmonella infections caused by two common strains. Researchers are giving the vaccine to healthy adults, children, and infants in Ghana to check if it is safe and triggers a strong immune response. The ultimat…
Phase 2 • Sponsor: GlaxoSmithKline • Aim: Vaccine
Last updated Sep 04, 2026 00:00 UTC
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New vaccine aims to stop deadly salmonella strains
Vaccine CompletedThis study tested a new vaccine designed to protect against two types of Salmonella bacteria that cause serious infections like typhoid fever and invasive nontyphoidal Salmonella disease. The trial involved 155 healthy adults in Europe and Africa who received three doses of the v…
Phase 1/2 • Sponsor: GlaxoSmithKline • Aim: Vaccine
Last updated Jun 27, 2026 08:00 UTC