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Inherited retinal dystrophy
MONDO:0019118An instance of retinal degeneration that is caused by an inherited modification of the individual's genome.
Also known as: fundus dystrophy, familial retinal dystrophy, genetic retinal dystrophy, hereditary retinal degeneration, hereditary retinal dystrophy, inherited retinal dystrophy, retinal dystrophy
521 clinical trials for this condition and its sub-types, 41 tagged with Inherited retinal dystrophy itself.
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Sub-types of Inherited retinal dystrophy
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Age-related macular degeneration 190 trials · 334 incl. sub-types
15 sub-types
- Wet macular degeneration 159 trials
- Dry age related macular degeneration 91 trials
- Age related macular degeneration 1 0 trials
- Age related macular degeneration 10 0 trials
- Age related macular degeneration 11 0 trials
- Age related macular degeneration 12 0 trials
- Age related macular degeneration 14 0 trials
- Age related macular degeneration 2 0 trials
- Age related macular degeneration 4 0 trials
- Age related macular degeneration 6 0 trials
- Age related macular degeneration 7 0 trials
- Age related macular degeneration 8 0 trials
- Age related macular degeneration 9 0 trials
- Macular degeneration, age-related, 3 0 trials
- Macular dystrophy with central cone involvement 0 trials
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Retinitis pigmentosa 84 trials · 89 incl. sub-types
101 sub-types
- Retinitis pigmentosa 3 7 trials
- Retinitis pigmentosa 4 5 trials
- Retinitis pigmentosa 11 4 trials
- Retinitis pigmentosa 39 3 trials
- Retinitis pigmentosa 1 1 trial
- Retinitis pigmentosa 25 1 trial
- Retinitis pigmentosa 37 1 trial
- Retinitis pigmentosa 40 1 trial
- Retinitis pigmentosa 45 1 trial
- Retinitis pigmentosa 47 1 trial
- Retinitis pigmentosa Y-linked 1 trial
- Autosomal recessive pericentral pigmentary retinopathy 0 trials
- Cone-rod dystrophy 15 0 trials
- Cone-rod dystrophy 16 0 trials
- Cone-rod dystrophy 2 0 trials
- Dominant pericentral pigmentary retinopathy 0 trials
- Late-adult onset retinitis pigmentosa 0 trials
- Retinal dystrophy and obesity 0 trials
- Retinitis pigmentosa 10 0 trials
- Retinitis pigmentosa 100 0 trials
- Retinitis pigmentosa 12 0 trials
- Retinitis pigmentosa 13 0 trials
- Retinitis pigmentosa 14 0 trials
- Retinitis pigmentosa 17 0 trials
- Retinitis pigmentosa 18 0 trials
- Retinitis pigmentosa 19 0 trials
- Retinitis pigmentosa 2 0 trials
- Retinitis pigmentosa 20 0 trials
- Retinitis pigmentosa 22 0 trials
- Retinitis pigmentosa 23 0 trials
- Retinitis pigmentosa 24 0 trials
- Retinitis pigmentosa 26 0 trials
- Retinitis pigmentosa 27 0 trials
- Retinitis pigmentosa 28 0 trials
- Retinitis pigmentosa 29 0 trials
- Retinitis pigmentosa 30 0 trials
- Retinitis pigmentosa 31 0 trials
- Retinitis pigmentosa 32 0 trials
- Retinitis pigmentosa 33 0 trials
- Retinitis pigmentosa 34 0 trials
- Retinitis pigmentosa 35 0 trials
- Retinitis pigmentosa 36 0 trials
- Retinitis pigmentosa 38 0 trials
- Retinitis pigmentosa 41 0 trials
- Retinitis pigmentosa 42 0 trials
- Retinitis pigmentosa 43 0 trials
- Retinitis pigmentosa 44 0 trials
- Retinitis pigmentosa 46 0 trials
- Retinitis pigmentosa 48 0 trials
- Retinitis pigmentosa 49 0 trials
- Retinitis pigmentosa 50 0 trials
- Retinitis pigmentosa 51 0 trials
- Retinitis pigmentosa 53 0 trials
- Retinitis pigmentosa 54 0 trials
- Retinitis pigmentosa 55 0 trials
- Retinitis pigmentosa 56 0 trials
- Retinitis pigmentosa 57 0 trials
- Retinitis pigmentosa 58 0 trials
- Retinitis pigmentosa 59 0 trials
- Retinitis pigmentosa 6 0 trials
- Retinitis pigmentosa 60 0 trials
- Retinitis pigmentosa 61 0 trials
- Retinitis pigmentosa 62 0 trials
- Retinitis pigmentosa 63 0 trials
- Retinitis pigmentosa 64 0 trials
- Retinitis pigmentosa 65 0 trials
- Retinitis pigmentosa 66 0 trials
- Retinitis pigmentosa 67 0 trials
- Retinitis pigmentosa 68 0 trials
- Retinitis pigmentosa 69 0 trials
- Retinitis pigmentosa 7 0 trials
- Retinitis pigmentosa 7, digenic 0 trials
- Retinitis pigmentosa 70 0 trials
- Retinitis pigmentosa 71 0 trials
- Retinitis pigmentosa 72 0 trials
- Retinitis pigmentosa 73 0 trials
- Retinitis pigmentosa 74 0 trials
- Retinitis pigmentosa 75 0 trials
- Retinitis pigmentosa 76 0 trials
- Retinitis pigmentosa 77 0 trials
- Retinitis pigmentosa 78 0 trials
- Retinitis pigmentosa 79 0 trials
- Retinitis pigmentosa 80 0 trials
- Retinitis pigmentosa 81 0 trials
- Retinitis pigmentosa 83 0 trials
- Retinitis pigmentosa 84 0 trials
- Retinitis pigmentosa 85 0 trials
- Retinitis pigmentosa 86 0 trials
- Retinitis pigmentosa 87 with choroidal involvement 0 trials
- Retinitis pigmentosa 88 0 trials
- Retinitis pigmentosa 9 0 trials
- Retinitis pigmentosa 90 0 trials
- Retinitis pigmentosa 92 0 trials
- Retinitis pigmentosa 93 0 trials
- Retinitis pigmentosa 94, variable age at onset 0 trials
- Retinitis pigmentosa 95 0 trials
- Retinitis pigmentosa 96 0 trials
- Retinitis pigmentosa 97 0 trials
- Retinitis pigmentosa 98 0 trials
- Retinitis pigmentosa 99 0 trials
- Retinitis pigmentosa with or without situs inversus 0 trials
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Hereditary macular dystrophy 3 trials · 70 incl. sub-types
17 sub-types
- Familial flecked retinopathy 0 trials · 43 incl. sub-types Sub-types →
- Macular corneal dystrophy 13 trials
- Vitelliform macular dystrophy 6 trials · 10 incl. sub-types Sub-types →
- Cone dystrophy 4 trials Sub-types →
- AICA-ribosiduria 1 trial
- Macular dystrophy, retinal 1 trial Sub-types →
- EEM syndrome 0 trials
- Benign concentric annular macular dystrophy 0 trials
- Coloboma of macula 0 trials
- Coloboma of macula-brachydactyly type B syndrome 0 trials
- Macular coloboma-cleft palate-hallux valgus syndrome 0 trials
- Macular dystrophy with or without cone dysfunction 0 trials
- Macular dystrophy, X-linked 0 trials
- Macular dystrophy, fenestrated sheen type 0 trials
- Occult macular dystrophy 0 trials
- Patterned dystrophy of the retinal pigment epithelium 0 trials Sub-types →
- Renal hypomagnesemia 5 with ocular involvement 0 trials
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Cone-rod dystrophy 17 trials · 21 incl. sub-types
28 sub-types
- X-linked cone-rod dystrophy 0 trials · 2 incl. sub-types Sub-types →
- Cone-rod dystrophy 10 1 trial
- Cone-rod dystrophy 6 1 trial
- Leber congenital amaurosis 4 0 trials
- Newfoundland cone-rod dystrophy 0 trials
- Cone dystrophy 3 0 trials
- Cone-rod dystrophy 1 0 trials
- Cone-rod dystrophy 11 0 trials
- Cone-rod dystrophy 12 0 trials
- Cone-rod dystrophy 13 0 trials
- Cone-rod dystrophy 14 0 trials
- Cone-rod dystrophy 15 0 trials
- Cone-rod dystrophy 16 0 trials
- Cone-rod dystrophy 17 0 trials
- Cone-rod dystrophy 18 0 trials
- Cone-rod dystrophy 19 0 trials
- Cone-rod dystrophy 2 0 trials
- Cone-rod dystrophy 20 0 trials
- Cone-rod dystrophy 21 0 trials
- Cone-rod dystrophy 22 0 trials
- Cone-rod dystrophy 24 0 trials
- Cone-rod dystrophy 3 0 trials
- Cone-rod dystrophy 5 0 trials
- Cone-rod dystrophy 7 0 trials
- Cone-rod dystrophy 8 0 trials
- Cone-rod dystrophy 9 0 trials
- Macular degeneration, X-linked atrophic 0 trials
- Retinal cone dystrophy 4 0 trials
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Leber congenital amaurosis 10 trials · 12 incl. sub-types
21 sub-types
- Leber congenital amaurosis 10 2 trials
- Leber congenital amaurosis 2 2 trials
- Leber congenital amaurosis 5 2 trials
- Leber congenital amaurosis 1 1 trial
- Leber congenital amaurosis 11 0 trials
- Leber congenital amaurosis 12 0 trials
- Leber congenital amaurosis 13 0 trials
- Leber congenital amaurosis 14 0 trials
- Leber congenital amaurosis 15 0 trials
- Leber congenital amaurosis 16 0 trials
- Leber congenital amaurosis 17 0 trials
- Leber congenital amaurosis 18 0 trials
- Leber congenital amaurosis 19 0 trials
- Leber congenital amaurosis 3 0 trials
- Leber congenital amaurosis 4 0 trials
- Leber congenital amaurosis 6 0 trials
- Leber congenital amaurosis 7 0 trials
- Leber congenital amaurosis 8 0 trials
- Leber congenital amaurosis 9 0 trials
- Leber congenital amaurosis with early-onset deafness 0 trials
- Retinal aplasia 0 trials
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ABCA4-related retinopathy 7 trials · 11 incl. sub-types
3 sub-types
- Severe early-childhood-onset retinal dystrophy 8 trials
- Cone-rod dystrophy 3 0 trials
- Retinitis pigmentosa 19 0 trials
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RPE65-related recessive retinopathy 5 trials · 7 incl. sub-types
2 sub-types
- Leber congenital amaurosis 2 2 trials
- Retinitis pigmentosa 20 0 trials
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BEST1-related dominant retinopathy 1 trial · 7 incl. sub-types
1 sub-type
- Vitelliform macular dystrophy 2 7 trials
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RHO-related retinopathy 0 trials · 7 incl. sub-types
2 sub-types
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RPGR-related retinopathy 0 trials · 7 incl. sub-types
3 sub-types
- Retinitis pigmentosa 3 7 trials
- X-linked cone-rod dystrophy 1 0 trials
- Macular degeneration, X-linked atrophic 0 trials
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Choroideremia 6 trials
2 sub-types
- Choroideremia hypopituitarism 0 trials
- Total central choroidal atrophy 0 trials
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X-linked retinoschisis 4 trials
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PRPF31-related retinopathy 1 trial · 4 incl. sub-types
1 sub-type
- Retinitis pigmentosa 11 4 trials
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RLBP1-related retinopathy 2 trials · 3 incl. sub-types
3 sub-types
- Fundus albipunctatus 1 trial Sub-types →
- Bothnia retinal dystrophy 0 trials
- Newfoundland cone-rod dystrophy 0 trials
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ELOVL4-related maculopathy 0 trials · 3 incl. sub-types
1 sub-type
- Stargardt disease 3 3 trials
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Revesz syndrome 2 trials
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Late-onset retinal degeneration 2 trials
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EYS-related retinopathy 1 trial · 2 incl. sub-types
1 sub-type
- Retinitis pigmentosa 25 1 trial
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LCA5-related retinopathy 1 trial · 2 incl. sub-types
1 sub-type
- Leber congenital amaurosis 5 2 trials
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PRPH2-related retinopathy 1 trial · 2 incl. sub-types
7 sub-types
- Fundus albipunctatus 1 trial Sub-types →
- Leber congenital amaurosis 18 0 trials
- Choroidal dystrophy, central areolar 2 0 trials
- Patterned macular dystrophy 1 0 trials
- Retinitis pigmentosa 7 0 trials
- Retinitis pigmentosa 7, digenic 0 trials
- Vitelliform macular dystrophy 3 0 trials
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BEST1-related recessive retinopathy 0 trials · 2 incl. sub-types
1 sub-type
- Autosomal recessive bestrophinopathy 2 trials
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AIPL1-related retinopathy 1 trial
1 sub-type
- Leber congenital amaurosis 4 0 trials
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Retinoschisis of fovea 1 trial
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ATF6-related retinopathy 0 trials · 1 incl. sub-types
1 sub-type
- Achromatopsia 7 1 trial
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CNGB1-related retinopathy 0 trials · 1 incl. sub-types
1 sub-type
- Retinitis pigmentosa 45 1 trial
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FLVCR1-related retinopathy with or without ataxia 0 trials · 1 incl. sub-types
1 sub-type
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GUCY2D retinopathy 0 trials · 1 incl. sub-types
3 sub-types
- GUCY2D-related recessive retinopathy 0 trials · 1 incl. sub-types Sub-types →
- Cone-rod dystrophy 6 1 trial
- GUCY2D-related dominant retinopathy 0 trials Sub-types →
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RDH5-related retinopathy 0 trials · 1 incl. sub-types
1 sub-type
- Fundus albipunctatus 1 trial Sub-types →
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ADAM9-related retinopathy 0 trials
1 sub-type
- Cone-rod dystrophy 9 0 trials
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CACNA1F-related retinopathy 0 trials
3 sub-types
- Aland island eye disease 0 trials
- X-linked cone-rod dystrophy 3 0 trials
- Congenital stationary night blindness 2A 0 trials
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CACNA2D4-related retinopathy 0 trials
1 sub-type
- Retinal cone dystrophy 4 0 trials
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CDHR1-related retinopathy 0 trials
3 sub-types
- Cone-rod dystrophy 15 0 trials
- Macular dystrophy, retinal, 5 0 trials
- Retinitis pigmentosa 65 0 trials
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CERKL-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 26 0 trials
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CNGA1-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 49 0 trials
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CNGA3-related retinopathy 0 trials
1 sub-type
- Achromatopsia 2 0 trials
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CRX-related retinopathy 0 trials
2 sub-types
- Leber congenital amaurosis 7 0 trials
- Cone-rod dystrophy 2 0 trials
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GNAT2-related retinopathy 0 trials
1 sub-type
- Achromatopsia 4 0 trials
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GPR179-related retinopathy 0 trials
1 sub-type
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GRM6-related retinopathy 0 trials
1 sub-type
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GUCA1A-related retinopathy 0 trials
2 sub-types
- Cone dystrophy 3 0 trials
- Cone-rod dystrophy 14 0 trials
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HGSNAT-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 73 0 trials
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IDH3B-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 46 0 trials
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IMPDH1-related retinopathy 0 trials
2 sub-types
- Leber congenital amaurosis 11 0 trials
- Retinitis pigmentosa 10 0 trials
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IMPG1-related dominant retinopathy 0 trials
1 sub-type
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IMPG1-related recessive retinopathy 0 trials
1 sub-type
- Vitelliform macular dystrophy 4 0 trials
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IMPG2-related dominant retinopathy 0 trials
1 sub-type
- Vitelliform macular dystrophy 5 0 trials
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IMPG2-related recessive retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 56 0 trials
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KCNV2-related retinopathy 0 trials
1 sub-type
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KIZ-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 69 0 trials
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LRIT3-related retinopathy 0 trials
1 sub-type
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MAK-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 62 0 trials
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MERTK-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 38 0 trials
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MRCS syndrome 0 trials
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NMNAT1-related retinopathy 0 trials
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NYX-related retinopathy 0 trials
1 sub-type
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Oguchi disease 0 trials
2 sub-types
- Oguchi disease-1 0 trials
- Oguchi disease-2 0 trials
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PCARE-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 54 0 trials
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PDE6A-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 43 0 trials
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PDE6C-related retinopathy 0 trials
1 sub-type
- Cone dystrophy 4 0 trials Sub-types →
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PDE6G-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 57 0 trials
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PROM1-related retinopathy 0 trials
3 sub-types
- PROM1-related dominant retinopathy 0 trials Sub-types →
- PROM1-related recessive retinopathy 0 trials Sub-types →
- Cone-rod dystrophy 12 0 trials
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PRPF8-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 13 0 trials
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RAB28-related retinopathy 0 trials
1 sub-type
- Cone-rod dystrophy 18 0 trials
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RD3-related retinopathy 0 trials
1 sub-type
- Leber congenital amaurosis 12 0 trials
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RDH12-related dominant retinopathy 0 trials
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RDH12-related recessive retinopathy 0 trials
1 sub-type
- Leber congenital amaurosis 13 0 trials
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REEP6-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 77 0 trials
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RP1-related dominant retinopathy 0 trials
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RP1-related recessive retinopathy 0 trials
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RP2-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 2 0 trials
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RPE65-related dominant retinopathy 0 trials
1 sub-type
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1 sub-type
- Retinitis pigmentosa 33 0 trials
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SPATA7-related retinopathy 0 trials
2 sub-types
- Leber congenital amaurosis 3 0 trials
- Retinitis pigmentosa 94, variable age at onset 0 trials
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Sorsby fundus dystrophy 0 trials
1 sub-type
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TOPORS-related retinopathy 0 trials
1 sub-type
- Retinitis pigmentosa 31 0 trials
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TRPM1-related retinopathy 0 trials
1 sub-type
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TTLL5-related retinopathy 0 trials
1 sub-type
- Cone-rod dystrophy 19 0 trials
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X-linked retinal dysplasia 0 trials
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Aceruloplasminemia 0 trials
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Amaurosis-hypertrichosis syndrome 0 trials
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Familial benign flecked retina 0 trials
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Macular degeneration, early-onset 0 trials
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Microcephaly and chorioretinopathy 1 0 trials
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Oligocone trichromacy 0 trials
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1 sub-type
- Basal laminar drusen 0 trials
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Retinoschisis, autosomal dominant 0 trials
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Vitreoretinal dystrophy 0 trials
Most studied deeper sub-types
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Can a single gene injection preserve sight in inherited blindness?
Cure Recruiting nowThis trial tests a gene therapy called SPVN20, given as a single injection into the eye, for people with advanced rod-cone dystrophy, a genetic condition that causes progressive vision loss. The study includes adults with a confirmed genetic diagnosis and some remaining cone cell…
Phase 1/2 • Sponsor: SparingVision • Aim: Cure
Last updated Sep 10, 2026 00:00 UTC
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Stem cell eye treatment could restore sight in retinal disease patients
Disease control Recruiting nowThis study tests a new treatment called OpCT-001 for people with inherited eye diseases that damage the retina, such as retinitis pigmentosa. The treatment involves injecting special photoreceptor cells, made from stem cells, into the back of the eye to replace lost cells. The tr…
Phase 1/2 • Sponsor: BlueRock Therapeutics • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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Bionic eye implant aims to bring back central sight in rare vision loss
Disease control Recruiting nowThis study tests a device called PRIMA, which is implanted under the retina to help people with inherited retinal diseases like Stargardt disease and retinitis pigmentosa see better. The trial will enroll 5 adults with severe central vision loss and measure improvements in visual…
Sponsor: Science Corporation • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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Could stem cells restore sight in damaged eyes?
Disease control Recruiting nowThis study tests whether injecting a person's own bone marrow stem cells into or near the eye can help treat various retinal and optic nerve diseases, including age-related macular degeneration, retinitis pigmentosa, and glaucoma. Participants receive stem cell injections via dif…
Sponsor: MD Stem Cells • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Experimental gene injection aims to save sight in rare retinal disorder
Disease control Recruiting nowThis early-phase trial tests a gene therapy called PUMCH-E111 for a rare inherited retinal disease caused by RLBP1 mutations. Six adults aged 18-55 will receive a single injection into the eye at a low or high dose. The main goal is to check safety, but researchers will also meas…
Early phase 1 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New pill hopes to tame rare ROSAH syndrome
Disease control Recruiting nowThis early-stage trial tests an oral drug called DF-003 in 12 people with ROSAH syndrome, a rare genetic condition causing eye inflammation, enlarged spleen, and headaches. The main goal is to check safety and how the body processes the drug, while also watching for improvements …
Phase 1 • Sponsor: Shanghai Yao Yuan Biotechnology Ltd. (also known as Drug Farm) • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Could an old drug save your sight? disulfiram trial targets vision loss
Disease control Recruiting nowThis study tests whether disulfiram, a drug already approved for alcohol dependence, can improve vision in people with inherited retinal degeneration. The drug aims to block a harmful signaling pathway in the retina that worsens vision loss. Thirty adults with the condition will …
Phase 1/2 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Gene therapy hope for kids and adults with rare Blindness-Causing mutation
Disease control Recruiting nowThis early-phase study tests a gene therapy called LX107 for people with a rare inherited eye disease caused by mutations in the AIPL1 gene. The treatment is given as an injection under the retina to try to improve vision and slow disease progression. The study will include 13 ad…
Early phase 1 • Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Alcoholism drug may boost vision in eye disease patients
Symptom relief Recruiting nowThis study looks at whether disulfiram (Antabuse), a drug used for alcohol use disorder, can improve vision in people with retinal degeneration (like macular degeneration or retinitis pigmentosa). Researchers believe it may calm overactive cells in the retina. The study involves …
Phase 1 • Sponsor: University of Rochester • Aim: Symptom relief
Last updated Sep 18, 2026 00:00 UTC
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Can talk therapy boost the benefits of low vision aids for people with inherited eye diseases?
Symptom relief Recruiting nowThis study tests whether adding emotional regulation therapy (ERT) to standard low vision rehabilitation (LVR) helps people with inherited retinal diseases who feel anxious or distressed about their vision. About 180 participants will receive LVR, which includes free vision-enhan…
Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Scientists seek genetic clues to mysterious fever diseases
Knowledge-focused Recruiting nowThis study aims to learn more about the genetics and natural history of autoinflammatory diseases, which cause repeated fevers and inflammation. Researchers will study up to 5,000 people, including patients, their relatives, and healthy volunteers. Participants provide blood and …
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Sep 11, 2026 00:00 UTC
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Massive study tracks rare eye diseases to pave way for future treatments
Knowledge-focused Recruiting nowThis international study aims to collect genetic and health information from 1,500 people with rare inherited retinal diseases like retinitis pigmentosa. It has two parts: a registry to gather genetic and vision data, and a natural history study that follows participants over tim…
Sponsor: Jaeb Center for Health Research • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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New eye camera could unlock secrets of inherited blindness
Knowledge-focused Recruiting nowThis study uses a special camera called an Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO) to take very detailed pictures of the retina in people with inherited retinal diseases like retinitis pigmentosa. Researchers will measure how the light-sensitive cells in the eye cha…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Eye zap study seeks to prove what patients already feel
Knowledge-focused Recruiting nowThis study looks at people with retinitis pigmentosa and similar eye diseases who already use a device called OkuStim® that sends mild electrical pulses to the eye. Many patients report temporary improvements in vision right after treatment, but these haven't been measured in a s…
Sponsor: Okuvision GmbH • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Eye camera showdown: can new tech match the gold standard?
Knowledge-focused Recruiting nowThis study compares two new ultrawide field cameras (Clarus and Optos) to the standard Spectralis camera for taking pictures of the back of the eye in people with inherited retinal diseases. Fifty adults will have their eyes dilated and photographed with all three cameras. The go…
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New study aims to sharpen vision tests for the blind
Knowledge-focused Recruiting nowThis study enrolls 25 people with severe retinal diseases like retinitis pigmentosa and Stargardt disease to test new ways of measuring visual function. Researchers will evaluate how well participants can perform various vision tests, such as navigating obstacles or detecting lig…
Sponsor: Ray Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Brain scans reveal how retinal disease rewires neural networks
Knowledge-focused Recruiting nowThis study uses MRI scans to look at how the brain's visual networks change in people with inherited retinal diseases. Researchers will scan 200 patients before and after they receive treatments like retinal implants or optogenetics. The goal is to understand how the brain adapts…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New color vision test could help people with severe vision loss
Knowledge-focused Recruiting nowThis study looks at how color vision changes over time in people with inherited retinal diseases (IRDs). Researchers will study 200 participants, including those with IRDs and healthy volunteers, to see how color vision loss relates to changes in the retina's structure. They are …
Sponsor: Zhongmou Therapeutics • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Pocket-Sized eye scanner could spot childhood blindness earlier
Knowledge-focused Recruiting nowThis study tests a new, ultracompact handheld eye scanner to take detailed pictures of the retina in children up to 8 years old with inherited retinal diseases. The goal is to see if this device can detect early signs of vision loss and help doctors monitor the disease over time.…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC