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New color vision test could help people with severe vision loss

NCT ID NCT07085533

Knowledge-focused Sponsor: Zhongmou Therapeutics Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how color vision changes over time in people with inherited retinal diseases (IRDs). Researchers will study 200 participants, including those with IRDs and healthy volunteers, to see how color vision loss relates to changes in the retina's structure. They are also testing a new color vision test designed for people with very low vision, which may be easier to use than current tests.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Individuals diagnosed with inherited retinal diseases (IRD) and non-IRD individuals

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Color Perception and Communication Ability Participants must have the ability to verbally identify or describe colors and test stimuli. This requires adequate cognitive and communicative capacity to understand instructions and respond appropriately during color vision testing. 2. Diagnosis of Inherited Retinal Dystrophy (IRD Group Only) Participants assigned to the IRD group must have a confirmed clinical diagnosis of an inherited retinal dystrophy 3. No Evidence of Inherited Retinal Disease (Control Group Only) Participants in the control group must have: * No known history or clinical evidence of inherited retinal degeneration * Normal retinal health or only non-retinal ocular conditions not affecting retinal function (e.g., mild cataract, corrected refractive error) * Normal or expected-normal color vision Exclusion Criteria: 1. Non retinal causes of color vision loss * Optic neuropathies (e.g., optic neuritis, glaucoma related optic nerve damage) * Cortical vision impairments affecting color perception * Any other neurological or optic nerve pathology causing color vision deficiency 2. Psychological or cognitive conditions affecting color perception or communication * Severe developmental delays * Cognitive impairments interfering with ability to comprehend or reliably perform color vision tests * Psychiatric conditions that impair visual interpretation or reliable testing 3. Prior treatment with potential transient effects on the retina * Recent retinal surgery * Recent drug therapy affecting retinal structure or function * Any acute intervention that might confound the correlation analyses due to lack of a stable baseline

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Conditions

The condition(s) this trial relates to.

achromatopsia Color Vision Defects color vision disorder inherited retinal dystrophy macular degeneration vision disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Achromatopsia Color vision defects Genotype Macular degeneration Mutation Optical coherence tomography (OCT) Phenotype Retinal dystrophies Vision disorders Visual acuity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Renmin Hospital of Wuhan University

    RECRUITING

    Wuhan, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.