Inherited epidermolysis bullosa
MONDO:0019276Inherited epidermolysis bullosa (EB) encompasses a number of disorders characterized by recurrent blister formation as the result of structural fragility within the skin and selected other tissues.
Also known as: epidermolysis bullosa hereditaria, hereditary epidermolysis bullosa
38 clinical trials for this condition and its sub-types, 5 tagged with Inherited epidermolysis bullosa itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Inherited epidermolysis bullosa
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Epidermolysis bullosa dystrophica 23 trials · 30 incl. sub-types
12 sub-types
- Recessive dystrophic epidermolysis bullosa 21 trials Sub-types →
- Generalized dominant dystrophic epidermolysis bullosa 1 trial
- Acral dystrophic epidermolysis bullosa 0 trials
- Centripetalis recessive dystrophic epidermolysis bullosa 0 trials
- Dystrophic epidermolysis bullosa pruriginosa 0 trials
- Dystrophic epidermolysis bullosa, nails only 0 trials
- Epidermolysis bullosa dystrophica Neurotrophica 0 trials
- Epidermolysis bullosa dystrophica with subcorneal cleavage 0 trials
- Localized dystrophic epidermolysis bullosa 0 trials
- Pretibial dystrophic epidermolysis bullosa 0 trials
- Recessive dystrophic epidermolysis bullosa-generalized other 0 trials
- Transient bullous dermolysis of the newborn 0 trials
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Junctional epidermolysis bullosa 6 trials · 8 incl. sub-types
15 sub-types
- Junctional epidermolysis bullosa, non-Herlitz type 2 trials Sub-types →
- Epidermolysis bullosa, junctional 2A, intermediate 0 trials
- Epidermolysis bullosa, junctional 2B, severe 0 trials
- Epidermolysis bullosa, junctional 3A, intermediate 0 trials
- Epidermolysis bullosa, junctional 3B, severe 0 trials
- Epidermolysis bullosa, junctional 4, intermediate 0 trials
- Epidermolysis bullosa, junctional 5A, intermediate 0 trials
- Epidermolysis bullosa, junctional 6, with pyloric atresia 0 trials
- Epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome 0 trials
- Junctional epidermolysis bullosa Herlitz type 0 trials
- Junctional epidermolysis bullosa inversa 0 trials
- Junctional epidermolysis bullosa with pyloric atresia 0 trials
- Laryngo-onycho-cutaneous syndrome 0 trials
- Late-onset junctional epidermolysis bullosa 0 trials
- Late-onset localized junctional epidermolysis bullosa-intellectual disability syndrome 0 trials
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Epidermolysis bullosa simplex 6 trials
20 sub-types
- Epidermolysis bullosa simplex 1B, generalized intermediate 1 trial
- Epidermolysis bullosa simplex 1C, localized 1 trial
- Epidermolysis bullosa simplex 1A, generalized severe 0 trials
- Epidermolysis bullosa simplex 1D, generalized, intermediate or severe, autosomal recessive 0 trials
- Epidermolysis bullosa simplex 2A, generalized severe 0 trials
- Epidermolysis bullosa simplex 2B, generalized intermediate 0 trials
- Epidermolysis bullosa simplex 2C, localized 0 trials
- Epidermolysis bullosa simplex 2E, with migratory circinate erythema 0 trials
- Epidermolysis bullosa simplex 2F, with mottled pigmentation 0 trials
- Epidermolysis bullosa simplex 2d, generalized, intermediate or severe, autosomal recessive 0 trials
- Epidermolysis bullosa simplex 3, localized or generalized intermediate, with BP230 deficiency 0 trials
- Epidermolysis bullosa simplex 4, localized or generalized intermediate, autosomal recessive 0 trials
- Epidermolysis bullosa simplex 5A, Ogna type 0 trials
- Epidermolysis bullosa simplex 5B, with muscular dystrophy 0 trials
- Epidermolysis bullosa simplex 5C, with pyloric atresia 0 trials
- Epidermolysis bullosa simplex 6, generalized, with scarring and hair loss 0 trials
- Epidermolysis bullosa simplex 7, with nephropathy and deafness 0 trials
- Epidermolysis bullosa simplex with anodontia/hypodontia 0 trials
- Epidermolysis bullosa simplex with nail dystrophy 0 trials
- Suprabasal epidermolysis bullosa simplex 0 trials Sub-types →
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Kindler syndrome 0 trials
1 sub-type
Most studied deeper sub-types
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Gene therapy skin graft aims to heal wounds in 'Butterfly Children'
Disease control Not yet recruitingThis trial evaluates a gene therapy skin graft called prademagene zamikeracel (pz-cel) for treating wounds in people with recessive dystrophic epidermolysis bullosa (RDEB), a severe genetic condition that causes fragile skin and chronic wounds. The study includes three parts: one…
Phase 4 • Sponsor: Abeona Therapeutics, Inc • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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New hope for blistering skin diseases: drug targets antibodies to heal wounds
Disease control Not yet recruitingThis early-phase study tests whether the drug efgartigimod (VYVGART) can lower harmful collagen VII antibodies and improve wound healing in people with two rare blistering skin conditions: recessive dystrophic epidermolysis bullosa (RDEB) and epidermolysis bullosa acquisita (EBA)…
Phase 1/2 • Sponsor: M. Peter Marinkovich • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New cream aims to soothe butterfly skin in Late-Stage trial
Symptom relief Not yet recruitingThis Phase 3 study tests the safety of SD-101 cream (6% allantoin) in 80 people with epidermolysis bullosa, a condition that causes fragile, blistering skin. Participants must have completed a prior study (SD-007). The main goal is to track any side effects over time.
Phase 3 • Sponsor: Paradigm Therapeutics • Aim: Symptom relief
Last updated Sep 11, 2026 00:00 UTC
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Can a birch bark gel soothe blistering skin disease?
Symptom relief Not yet recruitingThis pilot trial is testing whether a topical gel called Filsuvez, made from birch triterpenes, is safe and helpful for people aged 6 months and older with moderate-to-severe epidermolysis bullosa simplex (EBS), a condition causing fragile skin and blisters. Participants will app…
Phase 2 • Sponsor: Stanford University • Aim: Symptom relief
Last updated Aug 12, 2026 00:00 UTC
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Anti-Inflammatory drug may ease swallowing in rare skin disease
Symptom relief Not yet recruitingThis study investigates whether budesonide, an anti-inflammatory medication, can improve swallowing difficulties in people with dystrophic epidermolysis bullosa, a rare genetic condition that causes fragile skin and scarring. The researchers will review medical records of 15 pati…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC