Inflammatory bowel disease
MONDO:0005265A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.
Also known as: IBD, autoimmune bowel disorder, inflammatory bowel disease
1082 clinical trials for this condition and its sub-types, 430 tagged with Inflammatory bowel disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Inflammatory bowel disease
-
Colitis 41 trials · 679 incl. sub-types
9 sub-types
- Ulcerative colitis 581 trials Sub-types →
- Infectious colitis 0 trials · 69 incl. sub-types Sub-types →
- Indeterminate colitis 26 trials
- Proctocolitis 2 trials · 7 incl. sub-types Sub-types →
- Ileocolitis 5 trials
- Microscopic colitis 3 trials · 5 incl. sub-types Sub-types →
- Chemical colitis 3 trials
- Diversion colitis 2 trials
- Ischemic colitis 0 trials
-
Crohn disease 563 trials · 569 incl. sub-types
5 sub-types
- Small bowel Crohn disease 7 trials · 17 incl. sub-types Sub-types →
- Perianal Crohn disease 10 trials
- Crohn's colitis 7 trials
- Crohn disease of the esophagus 1 trial
- Oral Crohn disease 0 trials
-
Proctitis 2 trials · 21 incl. sub-types
2 sub-types
- Radiation proctitis 13 trials
- Proctocolitis 2 trials · 7 incl. sub-types Sub-types →
-
Inflammatory bowel disease 1 3 trials
-
Undetermined colitis 3 trials
-
Ulcerative proctosigmoiditis 2 trials
-
2 sub-types
- Inflammatory bowel disease 25 0 trials
- Inflammatory bowel disease 28 0 trials
-
Cap polyposis 0 trials
-
Inflammatory bowel disease 10 0 trials
-
Inflammatory bowel disease 11 0 trials
-
Inflammatory bowel disease 12 0 trials
-
Inflammatory bowel disease 13 0 trials
-
Inflammatory bowel disease 14 0 trials
-
Inflammatory bowel disease 15 0 trials
-
Inflammatory bowel disease 16 0 trials
-
Inflammatory bowel disease 17 0 trials
-
Inflammatory bowel disease 18 0 trials
-
Inflammatory bowel disease 19 0 trials
-
Inflammatory bowel disease 2 0 trials
-
Inflammatory bowel disease 20 0 trials
-
Inflammatory bowel disease 21 0 trials
-
Inflammatory bowel disease 22 0 trials
-
Inflammatory bowel disease 23 0 trials
-
Inflammatory bowel disease 24 0 trials
-
Inflammatory bowel disease 26 0 trials
-
Inflammatory bowel disease 27 0 trials
-
Inflammatory bowel disease 29 0 trials
-
Inflammatory bowel disease 3 0 trials
-
Inflammatory bowel disease 30 0 trials
-
Inflammatory bowel disease 4 0 trials
-
Inflammatory bowel disease 5 0 trials
-
Inflammatory bowel disease 6 0 trials
-
Inflammatory bowel disease 7 0 trials
-
Inflammatory bowel disease 8 0 trials
-
Inflammatory bowel disease 9 0 trials
-
2 sub-types
Most studied deeper sub-types
-
New daily pill aims to tame Crohn's Flare-Ups
Disease control Stopped earlyThis trial investigates whether an oral medication called etrasimod can help people with moderate to severe Crohn's disease who have not responded well to other treatments. Participants take either etrasimod or a placebo daily for up to several years. The study measures improveme…
Phase 2/3 • Sponsor: Pfizer • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
-
New biologic drug brazikumab tested for Crohn's – trial cut short
Disease control Stopped earlyThis study tested brazikumab, an experimental biologic drug, in 89 adults with moderate-to-severe Crohn's disease. Participants received either brazikumab, a placebo, or an active comparator (Humira) to see if the drug could improve symptoms and heal the gut lining. The trial was…
Phase 2/3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
-
New drug brazikumab aims to tame ulcerative colitis Flare-Ups
Disease control Stopped earlyThis phase 2 trial tested brazikumab in 242 adults with moderate-to-severe ulcerative colitis. Participants received either brazikumab or a placebo intravenously and then as injections over 54 weeks. The goal was to see if the drug could improve symptoms and heal the colon lining…
Phase 2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
-
Can IBD patients safely stretch their infusion schedule? new study tests two strategies
Disease control Stopped earlyThis study looks at people with inflammatory bowel disease (Crohn's disease or ulcerative colitis) who are in deep remission. It compares two methods for gradually increasing the time between infliximab infusions: one based on symptoms and one based on drug levels in the blood. T…
Sponsor: University Hospital, Montpellier • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
-
Crohn's drug trial halted early: what happened?
Disease control Stopped earlyThis study was designed to see if brazikumab is safe and tolerable over the long term for people with moderate to severe Crohn's disease. It enrolled 18 participants who had previously been in a related study. The trial was terminated early, meaning it did not reach its planned e…
Phase 3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
-
New hope for ulcerative colitis? drug trial shows promise
Disease control Stopped earlyThis study tested a drug called vixarelimab in 79 people with moderate to severe ulcerative colitis (UC) who had not responded well to other treatments. The goal was to see if the drug could help control the disease and reduce symptoms like diarrhea and bleeding. The study was st…
Phase 2 • Sponsor: Genentech, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
-
Pfizer's ulcerative colitis pill study halted early
Disease control Stopped earlyThis study tested an experimental oral drug, PF-07054894, in adults aged 18-75 with mild to severe ulcerative colitis (UC). The goal was to see if the drug could safely help control the disease and reduce symptoms like diarrhea and rectal bleeding. The trial was terminated early,…
Phase 1 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
-
Ulcerative colitis drug study halted early
Disease control Stopped earlyThis study looked at the safety and effectiveness of the drug ozanimod for people with moderate to severe ulcerative colitis. It aimed to see if the drug could improve symptoms like diarrhea and rectal bleeding, and how it affected quality of life. The study was terminated early,…
Phase 4 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
-
Diet study for Crohn's disease halted early – what we know
Disease control Stopped earlyThis study looked at whether an anti-inflammatory whole-food diet (rich in vegetables, fruits, and omega-3s, low in processed foods) could improve symptoms in people with mild to moderate Crohn's disease. It enrolled 28 adults and compared the diet to regular eating habits. The t…
Sponsor: University of California, Los Angeles • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
-
Mesh may stop hernias after stoma closure, but study halted early
Prevention Stopped earlyThis pilot study tested whether placing a special mesh during ileostomy closure surgery could prevent hernias in people with inflammatory bowel disease. Only 8 patients were enrolled before the study was stopped. The main goal was to check safety, like infections or wound problem…
Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Prevention
Last updated Jun 27, 2026 09:09 UTC
-
Exercise for IBD fatigue: tiny trial ends early
Symptom relief Stopped earlyThis study looked at whether moderate physical activity three times a week could reduce chronic fatigue in people with inflammatory bowel disease (IBD). Fatigue affects about 40% of IBD patients and can lower quality of life. The trial planned to compare a group that added extra …
Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
-
Buddy system for IBD teens: does a mentor make a difference?
Symptom relief Stopped earlyThis study looked at whether having a peer mentor—an older teen or young adult who also has IBD—can help youth ages 10-17 better manage their disease and improve their quality of life. Participants were randomly assigned to either a year-long mentoring program or educational acti…
Sponsor: Kelly Boone • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
-
Gut microbiome study in kids with autoimmune diseases ends early
Knowledge-focused Stopped earlyThis study aimed to compare the gut bacteria of children newly diagnosed with juvenile idiopathic arthritis, type 1 diabetes, or inflammatory bowel disease with those of their healthy siblings. Researchers wanted to see if differences in gut microbes and diet could explain why so…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC