Idiopathic pulmonary arterial hypertension
MONDO:0001999A sporadic form of pulmonary arterial hypertension (PAH) characterized by elevated pulmonary arterial resistance leading to right heart failure. IPAH is progressive and potentially fatal and not associated with an underlying condition or family history of PAH. The etiology is unknown.
Also known as: IPAH, idiopathic pulmonary arterial hypertension, primary pulmonary arterial hypertension, primary pulmonary hypertension
64 clinical trials for this condition and its sub-types, 15 tagged with Idiopathic pulmonary arterial hypertension itself.
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Can a traditional chinese herb pill help Lung-Heart patients breathe easier?
Disease control Recruiting nowThis study tests whether adding Qishen Yiqi Dropping Pills, a Chinese herbal medicine, to standard therapy can improve exercise ability and quality of life in 120 adults with severe pulmonary hypertension. Participants will be randomly assigned to receive either the herbal pills …
Sponsor: Guangdong Provincial People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Breathing in a special gas could help doctors see lung damage without needles
Diagnosis Recruiting nowThis study tests whether inhaling a special form of xenon gas during an MRI can help doctors see and measure blood vessel changes in the lungs of people with pulmonary arterial hypertension (PAH). The goal is to find a non-invasive way to diagnose different types of PAH and track…
Phase 2 • Sponsor: Bastiaan Driehuys • Aim: Diagnosis
Last updated Jun 27, 2026 09:07 UTC
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New PET tracer could spot deadly lung disease years earlier
Diagnosis Recruiting nowThis early-phase study tests whether a special PET scan tracer, 18F-fluoroglutamine, can detect pulmonary arterial hypertension (PAH) earlier and more accurately. PAH is a serious disease of the lung's blood vessels that often goes undiagnosed for years. The study will scan 71 ad…
Early phase 1 • Sponsor: Stephen Y. Chan • Aim: Diagnosis
Last updated Jun 27, 2026 08:13 UTC
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Fat in the heart: new clues for PAH?
Knowledge-focused Recruiting nowThis study examines why fat accumulates in the right ventricle of people with pulmonary arterial hypertension (PAH) and how it affects heart function and exercise ability. Researchers will use MRI and blood tests in 75 adults with PAH to track changes over time. The goal is to be…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New study seeks clues to why some get PAH and others Don't
Knowledge-focused Recruiting nowThis study is looking at people with pulmonary arterial hypertension (PAH), those with a genetic risk but no disease, and healthy individuals. Researchers aim to find molecular and physical markers that explain why some people get PAH and others stay healthy. The goal is to impro…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Scientists probe hidden links between hormones and lung disease
Knowledge-focused Recruiting nowThis study looks at how hormones and metabolism are involved in pulmonary arterial hypertension (PAH), a serious lung condition. Researchers will measure sex hormone levels, insulin resistance, and test two potential treatments—metformin and ACE-2—in small groups. The goal is to …
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:37 UTC