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Fat in the heart: new clues for PAH?

NCT ID NCT05462574

First seen Jun 08, 2026 · Last updated Jun 23, 2026 · Updated 2 times

Summary

This study examines why fat accumulates in the right ventricle of people with pulmonary arterial hypertension (PAH) and how it affects heart function and exercise ability. Researchers will use MRI and blood tests in 75 adults with PAH to track changes over time. The goal is to better understand the disease, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could point toward new ways to monitor or treat PAH by targeting fat accumulation in the heart.

What could go wrong

This is an observational study, not a treatment trial. It is small (75 people) and early-stage, so findings may not lead to direct therapies.

Conditions

The condition(s) this trial relates to.

drug- or toxin-induced pulmonary arterial hypertension Familial Primary Pulmonary Hypertension heritable pulmonary arterial hypertension idiopathic pulmonary arterial hypertension pulmonary arterial hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.