Fat in the heart: new clues for PAH?

NCT ID NCT05462574

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study examines why fat accumulates in the right ventricle of people with pulmonary arterial hypertension (PAH) and how it affects heart function and exercise ability. Researchers will use MRI and blood tests in 75 adults with PAH to track changes over time. The goal is to better understand the disease, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this research could point toward new ways to monitor or treat PAH by targeting fat accumulation in the heart.
What could go wrong
This is an observational study, not a treatment trial. It is small (75 people) and early-stage, so findings may not lead to direct therapies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

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