Hypertension, pregnancy-induced

This trial tests whether treating high blood pressure in pregnancy to a stricter target (below 140/90) is better than the usual approach (below 160/110) for women with gestational hypertension or preeclampsia without severe features. About 4,120 pregnant women will be randomly as…

This study tests a program for new mothers who had high blood pressure during pregnancy. Participants wear a FitBit and receive weekly messages with personalized activity goals. The goal is to see if this approach increases daily steps and improves blood pressure, and whether mom…

This pilot study tests whether giving new mothers with preeclampsia or gestational hypertension a blood pressure cuff, extra education, and a reminder bracelet helps them manage their blood pressure at home. About 40 participants will receive these tools before leaving the hospit…

This trial tests whether a low-sodium diet can improve blood pressure control in people who had a hypertensive disorder of pregnancy. Participants receive either a provided diet with less than 2000 mg of sodium per day or a standard diet with no salt restrictions for the first we…

This pilot study tests whether adding dipyridamole, an approved drug that improves blood flow, to standard care is feasible and safe for pregnant women with early-onset preeclampsia. The trial will enroll 15 hospitalized women between 26 and 34 weeks of pregnancy with high levels…

This study tests whether a patient navigator — a trained staff member who helps connect people with health services — can improve long-term heart health for those who had high blood pressure disorders during pregnancy. About 60 participants will be randomly assigned to receive ei…

This pilot study will test whether having pregnant women with chronic hypertension measure their blood pressure at home and adjust medications remotely can lead to better outcomes than standard in-office checks. Fifty participants will be randomly assigned to remote monitoring or…

This trial investigates whether a diet rich in polyphenols—including daily cocoa and extra fruits and vegetables—can reduce oxidative stress and improve blood vessel function in pregnant women. Researchers will randomly assign 60 pregnant women to receive dietary counseling and c…

This study tests whether combining a Bluetooth blood pressure monitor with regular support from a community health worker can help Black women control high blood pressure after pregnancy. About 404 women will be randomly assigned to either this extra support or standard care. The…

The ROOT study is testing a personalized nutrition program for pregnant women. Participants receive standard prenatal care plus customized diet and lifestyle plans based on their genes and nutrient levels. The goal is to see if this approach can lower the chances of preterm birth…

Researchers at Assiut University are testing whether a new ultrasound measurement, the Amniotic-Umbilical-to-Cerebral Ratio (AUCR), can predict complications in newborns of women with hypertensive disorders of pregnancy. They will compare AUCR with the traditional Cerebroplacenta…

This trial tests whether pairing women who had high blood pressure during or after pregnancy with a trained community health worker for six months can lower their blood pressure compared to usual care. Participants are randomly assigned to receive either standard care or standard…

This study tests a personalized support program called PTBCARE+ for pregnant individuals at high risk of delivering early. The program includes a stress reduction toolkit, a website/app, care coordination, and optional massage. Researchers will compare stress levels and birth out…

This study tests whether notifying obstetric clinicians when a pregnant patient is at high risk for preeclampsia increases the use of low-dose aspirin, which can help prevent the condition. Researchers will compare clinics that receive these alerts to those that continue usual ca…

This study tests whether a higher dose of aspirin (150mg) is better than the usual dose (75mg) at preventing preeclampsia, a serious condition involving high blood pressure during pregnancy. The trial will include 86 pregnant women in Kathmandu who are at high risk based on a sco…

Researchers are testing whether a structured prenatal education program based on the Roy Adaptation Model can reduce stress and improve quality of life for pregnant women with hypertensive disorders. The study enrolls 54 pregnant women between 20 and 32 weeks of gestation who hav…

This pilot trial tests whether a 12-week home-based exercise program, called ASK, is feasible and beneficial for postpartum women who had high blood pressure during pregnancy. The program combines aerobic exercise, strength training, and Kegel exercises, guided by a mobile app an…

This study looks at 40 mothers and their 6-month-old babies to see if mindfulness training during pregnancy helps them handle stress better together. Researchers will measure heart rate and stress responses during a short separation-and-reunion task. They will then check if these…

This study will follow 120 pregnant women with high blood pressure or preeclampsia to see if certain ultrasound scans and blood tests can predict who will develop severe disease. Researchers will measure blood flow in the mother's heart, eyes, and womb, along with lung ultrasound…