Hyperostosis

This study tests whether a newer type of dialysis filter (medium cut-off membrane) can better manage bone and mineral problems common in people with end-stage kidney disease. Thirty adults on maintenance dialysis will try both the new and standard filters for three months each. R…

This study compares two types of spinal fusion cages used in back surgery: a new titanium cage with a special rough surface and a standard plastic cage. About 100 adults with spine problems like narrowing of the spinal canal or slipped vertebrae will be randomly assigned to recei…

This study follows people who carry a gene mutation that puts them at high risk for Paget's disease of the bone. They previously received either zoledronic acid or a placebo in the ZiPP trial. Now researchers will track them for another 5 years to see if the drug can prevent or d…

This study compares two treatments for plantar fasciitis, a common cause of heel pain. One group will receive shockwave therapy, a costly procedure, while the other will get myofascial release, a hands-on massage technique. Researchers want to see if the cheaper option works just…

This study looks at how different types of dialysis affect heart health, bone metabolism, inflammation, and quality of life in people with end-stage kidney disease. Researchers will compare patients on hemodialysis, continuous ambulatory peritoneal dialysis, and automated periton…

This study looks at whether a genetic test can predict who will develop Paget's disease of the bone, a condition that can cause pain, deformity, and hearing loss. Researchers are studying 135 people aged 45 and older who have a parent or sibling with Paget's but do not have the d…