Hereditary skin disorder
MONDO:0100118An instance of skin disease that is caused by a modification of the individual's genome.
Also known as: disease, genetic skin, diseases, genetic skin, genetic skin disease, genetic skin diseases, genodermatosis, skin disease, genetic
880 clinical trials for this condition and its sub-types, 7 tagged with Hereditary skin disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Hereditary skin disorder
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Psoriasis 379 trials
3 sub-types
- Pustular psoriasis 6 trials · 39 incl. sub-types Sub-types →
- Guttate psoriasis 2 trials
- Psoriasis 2 0 trials
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Acne 91 trials
1 sub-type
- Adult acne 0 trials
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Hereditary angioedema 58 trials · 60 incl. sub-types
10 sub-types
- Hereditary angioedema with C1Inh deficiency 14 trials · 32 incl. sub-types Sub-types →
- Hereditary angioedema type 3 2 trials
- Hereditary angioedema with normal C1Inh 2 trials
- PLG-related hereditary angioedema with normal C1inh 0 trials
- Angioedema, hereditary, 4 0 trials
- Angioedema, hereditary, 5 0 trials
- Angioedema, hereditary, 6 0 trials
- Angioedema, hereditary, 7 0 trials
- Angioedema, hereditary, 8 0 trials
- Hereditary angioedema with normal C1inh not related to F12 or PLG variant 0 trials
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Ectodermal dysplasia syndrome 3 trials · 45 incl. sub-types
120 sub-types
- Dyskeratosis congenita 12 trials Sub-types →
- CTSC-related disorder 0 trials · 11 incl. sub-types Sub-types →
- Cardiofaciocutaneous syndrome 7 trials Sub-types →
- Anhidrotic ectodermal dysplasia-immunodeficiency-osteopetrosis-lymphedema syndrome 4 trials
- Incontinentia pigmenti 3 trials
- Ectodermal dysplasia WNT10A related 0 trials · 2 incl. sub-types Sub-types →
- Trichothiodystrophy 2 trials Sub-types →
- Cronkhite-Canada syndrome 1 trial
- Ellis-van Creveld syndrome 1 trial Sub-types →
- Cartilage-hair hypoplasia 1 trial Sub-types →
- Hypohidrotic ectodermal dysplasia 1 trial Sub-types →
- Trichorhinophalangeal syndrome 0 trials · 1 incl. sub-types Sub-types →
- ADULT syndrome 0 trials
- AREDYLD syndrome 0 trials
- Ackerman syndrome 0 trials
- Barber-Say syndrome 0 trials
- Bartsocas-Papas syndrome 1 0 trials
- Brunoni syndrome 0 trials
- Böök syndrome 0 trials
- CHIME syndrome 0 trials
- Clouston syndrome 0 trials
- Curly hair - acral keratoderma - caries syndrome 0 trials
- Dahlberg-Borer-Newcomer syndrome 0 trials
- Dubowitz syndrome 0 trials
- EEM syndrome 0 trials
- Fontaine progeroid syndrome 0 trials
- Fried's tooth and nail syndrome 0 trials
- GAPO syndrome 0 trials
- Ito hypomelanosis 0 trials
- Johnson neuroectodermal syndrome 0 trials
- KID syndrome 0 trials Sub-types →
- Lelis syndrome 0 trials
- Leukomelanoderma-infantilism-intellectual disability-hypodontia-hypotrichosis syndrome 0 trials
- Marshall syndrome 0 trials
- Naegeli-Franceschetti-Jadassohn syndrome 0 trials
- Rapp-Hodgkin syndrome 0 trials
- Schinzel-Giedion syndrome 0 trials
- Stern-Lubinsky-Durrie syndrome 0 trials
- Teebi-Shaltout syndrome 0 trials
- Toriello-Lacassie-Droste syndrome 0 trials
- Acrofacial dysostosis, Weyers type 0 trials
- Alopecia - contractures - dwarfism - intellectual disability syndrome 0 trials
- Alves Castelo dos Santos syndrome 0 trials
- Amelocerebrohypohidrotic syndrome 0 trials
- Ameloonychohypohidrotic syndrome 0 trials
- Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome 0 trials Sub-types →
- Anonychia with flexural pigmentation 0 trials
- Arrhythmogenic cardiomyopathy with wooly hair and keratoderma 0 trials
- Arthrogryposis-ectodermal dysplasia-other anomalies syndrome 0 trials
- Autosomal dominant palmoplantar keratoderma and congenital alopecia 0 trials
- Autosomal dominant trichoodontoonychodysplasia-syndactyly 0 trials
- Autosomal recessive palmoplantar keratoderma and congenital alopecia 0 trials
- Blepharocheilodontic syndrome 0 trials Sub-types →
- Cataract-hypertrichosis-intellectual disability syndrome 0 trials
- Cerebellar ataxia-ectodermal dysplasia syndrome 0 trials
- Chondroectodermal dysplasia with night blindness 0 trials
- Choroidal atrophy-alopecia syndrome 0 trials
- Circumscribed palmoplantar hypokeratosis 0 trials
- Cleft lip/palate-ectodermal dysplasia syndrome 0 trials
- Conductive deafness-ptosis-skeletal anomalies syndrome 0 trials
- Congenital hypotrichosis with juvenile macular dystrophy 0 trials
- Contractures-ectodermal dysplasia-cleft lip/palate syndrome 0 trials
- Cranioectodermal dysplasia 0 trials Sub-types →
- Dermatoosteolysis, Kirghizian type 0 trials
- Dermatopathia pigmentosa reticularis 0 trials
- Dermo-odonto dysplasia 0 trials
- Dermotrichic syndrome 0 trials
- Ectodermal dysplasia 12, hypohidrotic/hair/tooth/nail type 0 trials
- Ectodermal dysplasia 13, hair/tooth type 0 trials
- Ectodermal dysplasia 14, hair/tooth type with or without hypohidrosis 0 trials
- Ectodermal dysplasia 15, hypohidrotic/hair type 0 trials
- Ectodermal dysplasia 17 with or without limb malformations 0 trials
- Ectodermal dysplasia 5, hair/nail type 0 trials
- Ectodermal dysplasia Bartalos type 0 trials
- Ectodermal dysplasia alopecia preaxial polydactyly 0 trials
- Ectodermal dysplasia arthrogryposis diabetes mellitus 0 trials
- Ectodermal dysplasia blindness 0 trials
- Ectodermal dysplasia margarita type 0 trials
- Ectodermal dysplasia neurosensory deafness 0 trials
- Ectodermal dysplasia with natal teeth, Turnpenny type 0 trials
- Ectodermal dysplasia, trichoodontoonychial type 0 trials
- Ectodermal dysplasia-blindness syndrome 0 trials
- Ectodermal dysplasia-intellectual disability-central nervous system malformation syndrome 0 trials
- Ectodermal dysplasia-sensorineural deafness syndrome 0 trials
- Ectodermal dysplasia-syndactyly syndrome 0 trials Sub-types →
- Epidermolysis bullosa simplex due to plakophilin deficiency 0 trials
- Focal facial dermal dysplasia 0 trials Sub-types →
- Gingival fibromatosis-hypertrichosis syndrome 0 trials
- Hidrotic ectodermal dysplasia, Christianson-Fourie type 0 trials
- Hidrotic ectodermal dysplasia, Halal type 0 trials
- Hypertrichosis cubiti-short stature syndrome 0 trials
- Hypertrichosis lanuginosa congenita 0 trials Sub-types →
- Hypohidrotic ectodermal dysplasia-hypothyroidism-ciliary dyskinesia syndrome 0 trials
- Hypotrichosis-osteolysis-periodontitis-palmoplantar keratoderma syndrome 0 trials
- Ichthyosis-alopecia-eclabion-ectropion-intellectual disability syndrome 0 trials
- Jones hersh yusk syndrome 0 trials
- Limb-mammary syndrome 0 trials
- Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies 0 trials
- Nail and teeth abnormalities-marginal palmoplantar keratoderma-oral hyperpigmentation syndrome 0 trials
- Oculodentodigital dysplasia 0 trials Sub-types →
- Oculoosteocutaneous syndrome 0 trials
- Oculotrichodysplasia 0 trials
- Odonto-onycho dysplasia-alopecia syndrome 0 trials
- Odonto-tricho-ungual-digito-palmar syndrome 0 trials
- Odontomicronychial dysplasia 0 trials
- Odontotrichomelic syndrome 0 trials
- Pili torti-onychodysplasia syndrome 0 trials
- Pilodental dysplasia-refractive errors syndrome 0 trials
- Pure hair and nail ectodermal dysplasia 0 trials Sub-types →
- Scalp-ear-nipple syndrome 0 trials
- Taurodontia-absent teeth-sparse hair syndrome 0 trials
- Tooth and nail syndrome 0 trials
- Tricho-dento-osseous syndrome 0 trials
- Tricho-oculo-dermo-vertebral syndrome 0 trials
- Tricho-retino-dento-digital syndrome 0 trials
- Trichodental syndrome 0 trials
- Trichodermodysplasia-dental alterations syndrome 0 trials
- Trichodysplasia-amelogenesis imperfecta syndrome 0 trials
- Trichomegaly-retina pigmentary degeneration-dwarfism syndrome 0 trials
- Trichoodontoonychial dysplasia 0 trials
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CHILD syndrome 37 trials
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Inherited epidermolysis bullosa 5 trials · 37 incl. sub-types
4 sub-types
- Epidermolysis bullosa dystrophica 23 trials · 30 incl. sub-types Sub-types →
- Junctional epidermolysis bullosa 6 trials · 8 incl. sub-types Sub-types →
- Epidermolysis bullosa simplex 5 trials Sub-types →
- Kindler syndrome 0 trials Sub-types →
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Inherited ichthyosis 6 trials · 32 incl. sub-types
13 sub-types
- Netherton syndrome 15 trials
- Autosomal recessive congenital ichthyosis 2 trials · 10 incl. sub-types Sub-types →
- Keratinopathic ichthyosis 0 trials · 7 incl. sub-types Sub-types →
- Ichthyosis vulgaris 3 trials Sub-types →
- Recessive X-linked ichthyosis 2 trials Sub-types →
- Peeling skin syndrome 1 trial Sub-types →
- IFAP syndrome 0 trials Sub-types →
- Congenital cataract-ichthyosis syndrome 0 trials
- Ichthyosis hystrix 0 trials Sub-types →
- Ichthyosis linearis circumflexa 0 trials
- Ichthyosis with erythrokeratoderma 0 trials
- Ichthyosis-oral and digital anomalies syndrome 0 trials
- Neonatal ichthyosis-sclerosing cholangitis syndrome 0 trials
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Hereditary photodermatosis 0 trials · 31 incl. sub-types
6 sub-types
- Inherited porphyria 0 trials · 24 incl. sub-types Sub-types →
- Xeroderma pigmentosum 4 trials · 6 incl. sub-types Sub-types →
- Xeroderma pigmentosum-Cockayne syndrome complex 1 trial · 2 incl. sub-types Sub-types →
- Rothmund-Thomson syndrome 1 trial Sub-types →
- Bloom syndrome 0 trials
- UV-sensitive syndrome 0 trials Sub-types →
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Lichen sclerosus et atrophicus 10 trials · 20 incl. sub-types
1 sub-type
- Vulvar lichen sclerosus 15 trials
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Hereditary lipodystrophy 2 trials · 17 incl. sub-types
11 sub-types
- Familial partial lipodystrophy 13 trials · 14 incl. sub-types Sub-types →
- Congenital generalized lipodystrophy 2 trials · 3 incl. sub-types Sub-types →
- Berardinelli-Seip congenital lipodystrophy 0 trials · 1 incl. sub-types Sub-types →
- Keppen-Lubinsky syndrome 0 trials
- SHORT syndrome 0 trials
- Wiedemann-Rautenstrauch syndrome 0 trials
- Lipoatrophy with diabetes, leukomelanodermic papules, liver steatosis, and hypertrophic cardiomyopathy 0 trials
- Lipodystrophy due to peptidic growth factors deficiency 0 trials
- Lipodystrophy-intellectual disability-deafness syndrome 0 trials
- Mandibuloacral dysplasia 0 trials Sub-types →
- Severe neurodegenerative syndrome with lipodystrophy 0 trials
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Hereditary palmoplantar keratoderma 0 trials · 13 incl. sub-types
8 sub-types
- Diffuse palmoplantar keratoderma 0 trials · 12 incl. sub-types Sub-types →
- Olmsted syndrome 1 trial Sub-types →
- Focal palmoplantar keratoderma 0 trials · 1 incl. sub-types Sub-types →
- Palmoplantar keratoderma, epidermolytic 0 trials · 1 incl. sub-types Sub-types →
- Alopecia congenita keratosis palmoplantaris 0 trials
- Palmoplantar keratoderma i, striate, focal, or diffuse 0 trials
- Palmoplantar keratoderma, nonepidermolytic, focal or diffuse 0 trials
- Punctate palmoplantar keratoderma 0 trials Sub-types →
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Familial multiple nevi flammei 12 trials
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Syndromic oculocutaneous albinism 0 trials · 12 incl. sub-types
4 sub-types
- Chediak-Higashi syndrome 9 trials
- Hermansky-Pudlak syndrome 4 trials Sub-types →
- Griscelli syndrome 2 trials · 3 incl. sub-types Sub-types →
- Oculocerebral hypopigmentation syndrome, Cross type 0 trials
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Cowden disease 11 trials
8 sub-types
- Cowden syndrome 1 1 trial
- Cowden syndrome 2 0 trials
- Cowden syndrome 3 0 trials
- Cowden syndrome 4 0 trials
- Cowden syndrome 5 0 trials
- Cowden syndrome 6 0 trials
- Cowden syndrome 7 0 trials
- Sacral hemangiomas multiple congenital abnormalities 0 trials
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Familial pityriasis rubra pilaris 10 trials
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Lentigo 8 trials
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Large congenital melanocytic nevus 7 trials
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Neutrophil actin dysfunction 6 trials
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Seborrheic keratosis 6 trials
5 sub-types
- Eyelid seborrheic keratosis 0 trials
- Inflamed seborrheic keratosis 0 trials
- Inverted follicular keratosis 0 trials Sub-types →
- Melanoacanthoma 0 trials
- Vulvar seborrheic keratosis 0 trials Sub-types →
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Alopecia, isolated 0 trials · 6 incl. sub-types
8 sub-types
- Alopecia universalis congenita 6 trials
- Alopecia areata 1 0 trials
- Alopecia areata 2 0 trials
- Alopecia, androgenetic, 1 0 trials
- Alopecia, androgenetic, 2 0 trials
- Alopecia, androgenetic, 3 0 trials
- Alopecia, congenital 0 trials
- Familial focal alopecia 0 trials
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CLOVES syndrome 5 trials
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Legius syndrome 5 trials
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Reticulate pigment disorder 0 trials · 5 incl. sub-types
3 sub-types
- Dowling-Degos disease 0 trials · 4 incl. sub-types Sub-types →
- Dyschromatosis symmetrica hereditaria 1 trial
- Reticulate acropigmentation of Kitamura 0 trials
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Chronic mucocutaneous candidiasis 4 trials
12 sub-types
- Autoimmune enteropathy and endocrinopathy - susceptibility to chronic infections syndrome 0 trials
- Candidiasis, familial, 1 0 trials
- Candidiasis, familial, 3 0 trials
- Candidiasis, familial, 4 0 trials
- Candidiasis, familial, 6 0 trials
- Candidiasis, familial, 8 0 trials
- Candidiasis, familial, 9 0 trials
- Chronic mucocutaneous candidiasis due to inhibition of lymphoblastic transformation 0 trials
- Chronic mucocutaneous candidiasis due to intrinsic defect in lymphoblastic transformation 0 trials
- Chronic mucocutaneous candidiasis due to lymphokine deficiency 0 trials
- Chronic mucocutaneous candidiasis due to monocyte chemotactic disorder 0 trials
- Immunodeficiency 51 0 trials
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Lamellar ichthyosis 4 trials
6 sub-types
- Autosomal recessive congenital ichthyosis 6 1 trial
- Autosomal recessive congenital ichthyosis 3 0 trials
- Autosomal recessive congenital ichthyosis 4A 0 trials Sub-types →
- Autosomal recessive congenital ichthyosis 5 0 trials
- Autosomal recessive congenital ichthyosis 8 0 trials
- Ichthyosis, lamellar, autosomal dominant 0 trials
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Oculocutaneous albinism 4 trials
9 sub-types
- Oculocutaneous albinism type 1 0 trials · 1 incl. sub-types Sub-types →
- Autosomal dominant oculocutaneous albinism 0 trials
- Oculocutaneous albinism type 2 0 trials
- Oculocutaneous albinism type 3 0 trials
- Oculocutaneous albinism type 4 0 trials
- Oculocutaneous albinism type 5 0 trials
- Oculocutaneous albinism type 6 0 trials
- Oculocutaneous albinism type 7 0 trials
- Oculocutaneous albinism type 8 0 trials
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Piebaldism 4 trials
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Hailey-Hailey disease 3 trials
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Aplasia cutis congenita 3 trials
3 sub-types
- Aplasia cutis autosomal recessive 0 trials
- Aplasia cutis congenita dominant 0 trials
- Aplasia cutis-myopia syndrome 0 trials
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Hereditary mucosal leukokeratosis 3 trials
2 sub-types
- White sponge nevus 1 0 trials
- White sponge nevus 2 0 trials
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Schwannomatosis 3 trials
4 sub-types
- 22q-related schwannomatosis 0 trials
- LZTR1-related schwannomatosis 0 trials
- SMARCB1-related schwannomatosis 0 trials
- Neurofibromatosis, type III, mixed central and peripheral 0 trials
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Maffucci syndrome 2 trials
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Sneddon syndrome 2 trials
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Blue rubber bleb nevus 2 trials
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Familial chilblain lupus 2 trials
2 sub-types
- Chilblain lupus 1 0 trials
- Chilblain lupus 2 0 trials
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Keratosis pilaris atrophicans 2 trials
4 sub-types
- Atrophoderma vermiculata 0 trials
- Keratosis follicularis spinulosa decalvans 0 trials Sub-types →
- Keratosis pilaris atrophicans faciei 0 trials
- Ulerythema ophryogenesis 0 trials
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Stiff skin syndrome 2 trials
1 sub-type
- Fascial dystrophy, congenital 0 trials
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Sweet syndrome 2 trials
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Tietz syndrome 1 trial
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Acrokeratosis verruciformis 1 trial
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3 sub-types
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3 sub-types
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Linear nevus sebaceous syndrome 1 trial
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Neurocutaneous melanocytosis 1 trial
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Nevus, epidermal 1 trial
1 sub-type
- Wooly hair nevus 0 trials
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Urticaria, aquagenic 1 trial
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Becker nevus syndrome 0 trials
1 sub-type
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Cobb syndrome 0 trials
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Darier disease 0 trials
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H syndrome 0 trials
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MEDNIK syndrome 0 trials
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PENS syndrome 0 trials
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Acrogeria 0 trials
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Albinism-hearing loss syndrome 0 trials
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1 sub-type
- Wrinkly skin syndrome 0 trials
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Dermatitis herpetiformis, familial 0 trials
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Dermatosis papulosa nigra 0 trials
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Encephalocraniocutaneous lipomatosis 0 trials
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Epidermodysplasia verruciformis 0 trials
1 sub-type
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Familial acanthosis nigricans 0 trials
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Familial acne inversa 0 trials
3 sub-types
- Acne inversa, familial, 1 0 trials
- Acne inversa, familial, 2 0 trials
- Acne inversa, familial, 3 0 trials
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Familial keratoacanthoma 0 trials
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Familial multiple discoid fibromas 0 trials
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Familial multiple fibrofolliculoma 0 trials
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Hereditary mucoepithelial dysplasia 0 trials
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Hydroa vacciniforme, familial 0 trials
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1 sub-type
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Isolated congenital adermatoglyphia 0 trials
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Isolated hyperchlorhidrosis 0 trials
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Juvenile hyaline fibromatosis 0 trials
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Lichen planus, familial 0 trials
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Lipoid proteinosis 0 trials
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Monilethrix 0 trials
3 sub-types
- Monilethrix-1 0 trials
- Monilethrix-2 0 trials
- Monilethrix-3 0 trials
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2 sub-types
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Nevus comedonicus syndrome 0 trials
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Phakomatosis pigmentokeratotica 0 trials
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Pilomatrixoma 0 trials
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Poikiloderma with neutropenia 0 trials
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Porokeratosis 0 trials
4 sub-types
- Disseminated superficial actinic porokeratosis 0 trials Sub-types →
- Linear porokeratosis 0 trials
- Porokeratosis of Mibelli 0 trials Sub-types →
- Porokeratosis plantaris palmaris et disseminata 0 trials
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Progressive osseous heteroplasia 0 trials
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Sebocystomatosis 0 trials
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Spinocerebellar ataxia type 34 0 trials
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Vasculitis, lymphocytic, nodular 0 trials
Most studied deeper sub-types
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Can a new injection calm severe eczema when creams fall short?
Disease control Recruiting nowThis study tests whether an investigational drug called tilrekimig, given as injections alongside medicated creams or ointments, can improve moderate-to-severe eczema (atopic dermatitis) in people aged 12 and older. Participants will be randomly assigned to receive either tilreki…
Phase 3 • Sponsor: Pfizer • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Lab-Grown skin patch could heal wounds in 'Butterfly Children'
Disease control Recruiting nowThis study tests a new skin graft made from a patient's own cells, genetically modified to produce a missing protein. It aims to safely heal wounds in 9 people with recessive dystrophic epidermolysis bullosa (RDEB), a rare disease that causes fragile, blistering skin. The graft i…
Phase 1/2 • Sponsor: CHU de Quebec-Universite Laval • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Scientists probe how eczema drugs alter skin microbes
Knowledge-focused Recruiting nowThis study examines how common eczema treatments, including antibiotics and bleach baths, change the types and amounts of bacteria on the skin. Researchers will compare people with eczema to healthy volunteers. The goal is to understand the skin microbiome better, not to test a n…
Phase 2 • Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC