Hereditary cerebellar ataxia
MONDO:0100310Cerebellar ataxia that is transmitted from parent to child.
Also known as: cerebellar hereditary ataxia, hereditary cerebellar ataxia
133 clinical trials for this condition and its sub-types, 0 tagged with Hereditary cerebellar ataxia itself.
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Sub-types of Hereditary cerebellar ataxia
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Autosomal recessive cerebellar ataxia 0 trials · 72 incl. sub-types
29 sub-types
- Autosomal recessive degenerative and progressive cerebellar ataxia 0 trials · 49 incl. sub-types Sub-types →
- Autosomal recessive metabolic cerebellar ataxia 0 trials · 10 incl. sub-types Sub-types →
- Autosomal recessive congenital cerebellar ataxia 0 trials · 7 incl. sub-types Sub-types →
- Autosomal recessive syndromic cerebellar ataxia 0 trials · 2 incl. sub-types Sub-types →
- Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 0 trials · 2 incl. sub-types Sub-types →
- Charlevoix-Saguenay spastic ataxia 1 trial
- Autosomal recessive spinocerebellar ataxia 7 1 trial
- Lichtenstein-Knorr syndrome 0 trials
- RIDDLE syndrome 0 trials
- Ataxia with oculomotor apraxia type 3 0 trials
- Autosomal recessive ataxia due to ubiquinone deficiency 0 trials
- Autosomal recessive ataxia, Beauce type 0 trials
- Autosomal recessive cerebellar ataxia - epilepsy - intellectual disability syndrome 0 trials Sub-types →
- Autosomal recessive spinocerebellar ataxia 10 0 trials
- Autosomal recessive spinocerebellar ataxia 14 0 trials
- Autosomal recessive spinocerebellar ataxia 16 0 trials
- Autosomal recessive spinocerebellar ataxia 20 0 trials
- Infantile-onset autosomal recessive nonprogressive cerebellar ataxia 0 trials
- Spinocerebellar ataxia, autosomal recessive 22 0 trials
- Spinocerebellar ataxia, autosomal recessive 24 0 trials
- Spinocerebellar ataxia, autosomal recessive 25 0 trials
- Spinocerebellar ataxia, autosomal recessive 26 0 trials
- Spinocerebellar ataxia, autosomal recessive 27 0 trials
- Spinocerebellar ataxia, autosomal recessive 28 0 trials
- Spinocerebellar ataxia, autosomal recessive 29 0 trials
- Spinocerebellar ataxia, autosomal recessive 30 0 trials
- Spinocerebellar ataxia, autosomal recessive 31 0 trials
- Spinocerebellar ataxia, autosomal recessive 32 0 trials
- Spinocerebellar ataxia, autosomal recessive 33 0 trials
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Autosomal dominant cerebellar ataxia 11 trials · 33 incl. sub-types
15 sub-types
- Autosomal dominant cerebellar ataxia type I 0 trials · 16 incl. sub-types Sub-types →
- Autosomal dominant cerebellar ataxia type III 0 trials · 9 incl. sub-types Sub-types →
- Autosomal dominant cerebellar ataxia type IV 0 trials · 8 incl. sub-types Sub-types →
- Spinocerebellar ataxia 7 7 trials
- Spinocerebellar ataxia 27B, late-onset 4 trials
- Spinocerebellar ataxia 9 2 trials
- Spinocerebellar ataxia 27A 1 trial
- GRID2-related autosomal dominant spinocerebellar ataxia 0 trials
- Spinocerebellar ataxia 43 0 trials
- Spinocerebellar ataxia 44 0 trials
- Spinocerebellar ataxia 47 0 trials
- Spinocerebellar ataxia 48 0 trials
- Spinocerebellar ataxia 49 0 trials
- Spinocerebellar ataxia 50 0 trials
- Spinocerebellar ataxia 51 0 trials
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Ataxia telangiectasia 11 trials
1 sub-type
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X-linked cerebellar ataxia 0 trials
9 sub-types
- X-linked intellectual disability-ataxia-apraxia syndrome 0 trials
- X-linked non progressive cerebellar ataxia 0 trials
- X-linked progressive cerebellar ataxia 0 trials
- X-linked sideroblastic anemia with ataxia 0 trials
- X-linked spinocerebellar ataxia type 3 0 trials
- X-linked spinocerebellar ataxia type 4 0 trials
- Ataxia - deafness - intellectual disability syndrome 0 trials
- Fragile X-associated tremor/ataxia syndrome 0 trials
- Spinocerebellar ataxia, X-linked 2 0 trials
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Ataxia-pancytopenia syndrome 0 trials
Most studied deeper sub-types
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Can targeted brain zaps ease movement problems in a rare ataxia?
Disease control Not yet recruitingThis trial tests a non-invasive brain stimulation technique called transcranial temporal interference stimulation (tTIS) in people with spinocerebellar ataxia type 3, a genetic condition that affects coordination and balance. The stimulation targets a deep brain region involved i…
Sponsor: First Affiliated Hospital of Fujian Medical University • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Can diet and vitamin c supercharge rectal cancer treatment?
Disease control Not yet recruitingThis phase 2 trial is investigating whether adding a ketogenic diet and/or high-dose intravenous vitamin C to standard chemoradiotherapy and immunotherapy can improve outcomes for patients with locally advanced rectal cancer that is mismatch repair proficient (pMMR/MSS). The stud…
Phase 2 • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Experimental drug aims to halt rare neurological decline
Disease control Not yet recruitingThis Phase 3 trial tests whether vatiquinone can slow the progression of Friedreich's ataxia, a rare genetic disorder that damages the nervous system and impairs movement. About 120 adults with moderate symptoms will take the drug for 24 months. Researchers will measure changes i…
Phase 3 • Sponsor: PTC Therapeutics • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Can brain stimulation tame ataxia?
Disease control Not yet recruitingThis trial tests whether deep brain stimulation (DBS) targeting the cerebellum is safe and feasible for people with spinocerebellar ataxia types 1 and 3, a group of inherited disorders that cause progressive problems with movement and coordination. The study will enroll 12 adults…
Sponsor: Gordon H. Baltuch • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Could a simple gel boost gum healing in diabetes?
Disease control Not yet recruitingThis study tests whether adding hyaluronic acid gel to standard deep cleaning (scaling and root planing) improves gum healing in people with both diabetes and advanced gum disease. Twenty-three participants will receive the standard cleaning on all teeth, and then two gum pockets…
Sponsor: Marmara University • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New combo therapy aims to spare organs in High-Risk rectal cancer
Disease control Not yet recruitingThis phase 3 trial tests whether short-course radiation followed by chemotherapy and an immunotherapy drug (serplulimab) works better than standard long-course chemoradiation for high-risk locally advanced rectal cancer. 612 patients will be randomly assigned to one of the two tr…
Phase 3 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Could stem cells help people with spinocerebellar ataxia? new trial aims to find out
Disease control Not yet recruitingThis Phase 2 trial tests whether umbilical cord stem cells can safely improve movement and coordination in people with spinocerebellar ataxia (types 1, 2, 3, and 6). Forty-five participants will receive the cells through an IV and a spinal injection. The main goal is to see if sy…
Phase 2 • Sponsor: Sclnow Biotechnology Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Could stem cells help people with spinocerebellar ataxia?
Disease control Not yet recruitingThis early-stage trial tests whether stem cells and their exosomes (tiny particles that help cells communicate) can safely improve movement in people with spinocerebellar ataxia, a condition that affects coordination and balance. Ninety participants will receive the treatment thr…
Phase 1/2 • Sponsor: Biocells Medical • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Can intense walking training help brain injury patients walk better?
Symptom relief Not yet recruitingThis study looks at whether high-intensity walking training can help people with cerebellar damage (a part of the brain that controls balance and coordination) improve their walking ability. Twenty participants will either do intense walking exercises or standard training. The go…
Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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New therapy aims to ease grief after miscarriage or stillbirth
Symptom relief Not yet recruitingThis pilot study tests a 4-week program based on acceptance and commitment therapy (ACT) for women who have experienced a miscarriage, stillbirth, or newborn death within the past year. The program includes six sessions plus a booster, combining in-person and video meetings. Rese…
Sponsor: Second Xiangya Hospital of Central South University • Aim: Symptom relief
Last updated Jun 27, 2026 12:26 UTC
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Exercise and drug combo may fight fatigue in rare disease
Symptom relief Not yet recruitingThis study looks at whether doing aerobic exercise at home, with or without the drug omaveloxolone, can safely improve fatigue and heart-lung fitness in people with Friedreich's ataxia. About 30 adults with the condition will take part. The goal is to see if the combination helps…
Sponsor: Scott Barbuto • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Video games and AI join the fight against a rare movement disorder
Knowledge-focused Not yet recruitingThis study is testing whether a new digital tool—using AI-powered video games and a single camera—can accurately measure movement problems in people with Friedreich ataxia, a rare inherited condition that affects balance and coordination. Participants play short movement-based co…
Sponsor: University of Exeter • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Could early markers unlock treatments for a rare childhood disease?
Knowledge-focused Not yet recruitingThis study follows babies and young children (up to age 5) who have a genetic diagnosis of ataxia telangiectasia (A-T), a rare disease that affects movement and immunity. Researchers use brain and lung scans, blood tests, and movement analysis to spot early signs of disease progr…
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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AI vs. experts: can a computer judge speech as well as a human?
Knowledge-focused Not yet recruitingThis study will compare how well an AI program (Blings) measures speech clarity in 40 adults with speech disorders from stroke or other neurological conditions. Two speech therapists will also rate the same speech samples. The goal is to see if the AI can reliably replace or assi…
Sponsor: Pusan National University Yangsan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC