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Video games and AI join the fight against a rare movement disorder

NCT ID NCT07731971

Knowledge-focused Sponsor: University of Exeter Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This study is testing whether a new digital tool—using AI-powered video games and a single camera—can accurately measure movement problems in people with Friedreich ataxia, a rare inherited condition that affects balance and coordination. Participants play short movement-based computer games while AI software tracks their motions. The goal is to see if these game-based measurements are reliable and sensitive enough to be used in future clinical trials, potentially offering a more objective and patient-friendly alternative to standard rating scales.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
VR active gaming tasks and AI markerless motion capture
What this could lead to
If successful, this digital tool could provide a more sensitive, patient-friendly way to measure movement in future Friedreich ataxia trials, potentially speeding up drug development.
What could go wrong
This is an early feasibility study with only 40 participants. The digital measurements may not prove accurate or sensitive enough to replace existing clinical scales.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Study participants with FA spanning a range of disease severity and functional mobility, recruited across England, together with healthy volunteers of the same age range serving as a comparison group.

Ages

12 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Friedreich ataxia group: * Aged 12 to 50 years * Genetically confirmed Friedreich ataxia * Able to sit or stand independently for 5 minutes * Able to provide informed consent (or assent with parental consent if under 16 years) * Stable medication regimen (no changes in the past 4 weeks) Healthy control group: * Aged 12 to 50 years * No history of genetically confirmed Friedreich ataxia * Able to sit or stand independently for 5 minutes * Able to provide informed consent (or assent with parental consent if under 16 years) Exclusion Criteria: * Friedreich ataxia group: * Aged 11 years or younger, or 51 years or older * Severe cognitive impairment precluding task comprehension * Active seizure disorder, or vestibular dysfunction causing nausea with non-immersive VR * Currently participating in an interventional clinical trial * No reliable internet connection (where a digital inclusion pack cannot resolve this) * Any reason precluding safe participation in moderate-intensity exercise. Healthy control group: * Aged 11 years or younger, or 51 years or older * Genetically confirmed Friedreich ataxia * Any reason precluding safe participation in moderate-intensity exercise.

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Conditions

The condition(s) this trial relates to.

Friedreich ataxia Rare Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Friedreich ataxia

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University of Exeter

    Exeter, United Kingdom

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Other studies related to the condition(s) this trial covers.