Gram-negative bacterial infections
MONDO:0021678Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.
Also known as: bacterial infection, gram-negative, bacterial infections, gram negative, bacterial infections, gram-negative, bacterial infections, gramme negative, gram negative bacterial infections, gram-negative bacterial infection, gramme negative bacterial infections, infection, gram-negative bacterial
300 clinical trials for this condition and its sub-types, 33 tagged with Gram-negative bacterial infections itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Gram-negative bacterial infections
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Helicobacter pylori infectious disease 115 trials
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Treponema infectious disease 6 trials · 57 incl. sub-types
4 sub-types
- Syphilis 47 trials · 56 incl. sub-types Sub-types →
- Pinta disease 1 trial
- Syphilitic encephalitis 0 trials
- Syphilitic meningitis 0 trials
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Chlamydiaceae infections 1 trial · 55 incl. sub-types
1 sub-type
- Chlamydia infectious disease 34 trials · 55 incl. sub-types Sub-types →
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Bordetellosis 0 trials · 39 incl. sub-types
2 sub-types
- Pertussis 39 trials
- Bordetella parapertussis infectious disease 0 trials
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Moraxellaceae infectious disease 0 trials · 8 incl. sub-types
1 sub-type
- Acinetobacter infectious disease 8 trials
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Pneumonia caused by gram negative bacteria 5 trials · 7 incl. sub-types
2 sub-types
- Pneumonia caused by chlamydia 2 trials
- Rickettsial pneumonia 0 trials
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Rickettsiaceae infectious disease 0 trials · 4 incl. sub-types
3 sub-types
- Typhus 0 trials · 3 incl. sub-types Sub-types →
- Spotted fever 0 trials · 1 incl. sub-types Sub-types →
- Rickettsial pneumonia 0 trials
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Burkholderia infectious disease 0 trials · 3 incl. sub-types
3 sub-types
- Melioidosis 3 trials
- Cepacia syndrome 0 trials
- Glanders 0 trials
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Anaplasmataceae infectious disease 0 trials · 2 incl. sub-types
4 sub-types
- Ehrlichiosis 1 trial Sub-types →
- Human granulocytic anaplasmosis 1 trial
- Neorickettsia infectious disease 0 trials
- Sennetsu fever 0 trials
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Bartonellaceae infectious disease 0 trials · 1 incl. sub-types
1 sub-type
- Bartonellosis 0 trials · 1 incl. sub-types Sub-types →
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Bacteroidaceae infectious disease 0 trials
1 sub-type
- Bacteroides infectious disease 0 trials
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Fusobacteriaceae infectious disease 0 trials
1 sub-type
- Fusobacterium infectious disease 0 trials
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1 sub-type
- Syphilitic meningitis 0 trials
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Streptobacillus infectious disease 0 trials
1 sub-type
- Streptobacillary rat-bite fever 0 trials
Most studied deeper sub-types
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Could a simple pill replace IV drips for blood infections?
Disease control CompletedThis study tests whether stable patients with a common blood infection (gram-negative bacteraemia) can safely switch from IV antibiotics to oral pills within 72 hours. Researchers will compare early oral therapy to continued IV treatment in 720 adults. The main goal is to see if …
Phase 4 • Sponsor: Tan Tock Seng Hospital • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New antibiotic shows promise for newborns with dangerous infections
Disease control CompletedThis study looked at how the antibiotic cefiderocol works in hospitalized infants under 3 months old with suspected or confirmed gram-negative bacterial infections. Researchers measured drug levels in the blood and checked for side effects in 30 babies. The goal was to find the r…
Phase 2 • Sponsor: Shionogi • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New antibiotic shows promise for kids with tough infections
Disease control CompletedThis study tested the safety and how the body processes the antibiotic cefiderocol in hospitalized children aged 3 months to 18 years with serious bacterial infections. The goal was to see if the drug is safe and how it works in the body. 53 children participated, and the study i…
Phase 2 • Sponsor: Shionogi • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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New antibiotic shows promise for kids with tough infections
Disease control CompletedThis study tested a new antibiotic called MK-7655A in 115 children from birth to 18 years old who had serious bacterial infections. The goal was to see if the drug is safe and works better than standard treatments. Children were randomly assigned to receive either the new drug or…
Phase 2/3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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A 5-hour test may replace days of waiting for the right antibiotic in blood infections
Diagnosis CompletedThis trial tests whether a rapid diagnostic test called Reveal can improve outcomes for hospitalized patients with gram-negative bloodstream infections. The test measures bacterial growth by detecting gases they release, giving results in about 5 hours instead of the usual 2-3 da…
Sponsor: Duke University • Aim: Diagnosis
Last updated Jul 30, 2026 00:00 UTC
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Speedy bug ID: new tests aim to cut antibiotic guesswork in ICU blood infections
Knowledge-focused CompletedThis study tested whether three new diagnostic tools could help doctors pick the best antibiotic faster for ICU patients with Gram-negative bloodstream infections. Researchers compared standard lab methods to the new tests in 100 patients. The goal was to see if more patients got…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Can a simple kidney test help beat superbugs in the ICU?
Knowledge-focused CompletedThis study aims to see if using a blood marker called Cystatin C can better predict how antibiotics work in critically ill ICU patients with drug-resistant infections. Researchers will compare Cystatin C to standard kidney function tests and a dye-based gold-standard test. The go…
Phase 4 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC
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ICU antibiotic study reveals resistance risks
Knowledge-focused CompletedThis study examined whether giving ICU patients the same antibiotic they had before, versus a different one, affects the development of drug-resistant bacteria. Researchers looked at 197 adults with Gram-negative infections. The goal was to understand how antibiotic choice impact…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New antibiotic TQD3524 tested in kidney patients
Knowledge-focused CompletedThis early-stage study tested a single dose of the antibiotic TQD3524 in 48 people with varying degrees of kidney function. The goal was to see how the drug moves through the body and is removed, especially by the kidneys, and to check for any safety issues. The study did not aim…
Phase 1 • Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC