Could a simple pill replace IV drips for blood infections?
NCT ID NCT05199324
First seen Apr 17, 2026
Summary
This study tests whether stable patients with a common blood infection (gram-negative bacteraemia) can safely switch from IV antibiotics to oral pills within 72 hours. Researchers will compare early oral therapy to continued IV treatment in 720 adults. The main goal is to see if survival rates at 30 days are similar between the two groups.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GRAM-NEGATIVE BACTERAEMIA are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Tan Tock Seng Hospital
RECRUITINGSingapore, Singapore, 308433, Singapore
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oral fluoroquinolones (e.g., ciprofloxacin) or oral trimethoprim-sulfamethoxazole (Bactrim)
What this could lead to
If successful, this could show that switching to oral antibiotics early is as safe and effective as staying on IV therapy, potentially reducing hospital stays and treatment costs.
What could go wrong
This is a single-center trial, and results may not apply to all patients. The oral antibiotics may not work as well in sicker patients or those with hidden infection sources.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.