Goiter
MONDO:0005397Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing.
Also known as: Thyromegaly, goiter, goiter (disease), goitre (disease)
102 clinical trials for this condition and its sub-types, 12 tagged with Goiter itself.
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Sub-types of Goiter
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Toxic diffuse goiter 0 trials · 53 incl. sub-types
1 sub-type
- Graves disease 53 trials Sub-types →
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Nodular goiter 36 trials · 43 incl. sub-types
1 sub-type
- Multinodular goiter 10 trials Sub-types →
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Endemic goiter 4 trials
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Nontoxic goiter 1 trial
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Substernal goiter 1 trial
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Dyshormonogenic goiter 0 trials
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Lingual goiter 0 trials
Most studied deeper sub-types
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Glowing goggles could prevent calcium crash after thyroid surgery
Disease control Not yet recruitingThis study tests whether a wearable goggle system that makes parathyroid glands glow can help surgeons find and protect them during thyroid removal. About 280 adults having thyroid surgery will take part. The goal is to reduce the risk of low calcium levels after surgery, a commo…
Sponsor: Ss. Cyril and Methodius University of Skopje • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Herbal pills tested as possible treatment for thyroid nodules
Disease control Not yet recruitingThis phase 4 trial tests whether two traditional Chinese medicines, Xiaojin Pill and Neixiao Luoli Pill, can safely reduce the size of benign or low-risk thyroid nodules. About 108 adults aged 18 to 65 will be randomly assigned to take one of the pills or receive only lifestyle a…
Phase 4 • Sponsor: Zhejiang Provincial People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Could a vitamin before surgery prevent a common complication?
Prevention Not yet recruitingThis study tests whether taking vitamin D3 along with calcium for a week before total thyroidectomy prevents symptomatic low calcium levels after surgery better than calcium alone. 124 adults with multinodular goiter will be randomly assigned to one of the two groups. After surge…
Sponsor: King Edward Medical University • Aim: Prevention
Last updated Jun 27, 2026 12:36 UTC
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Two autoimmune conditions, one child: study probes hidden thyroid trouble
Knowledge-focused Not yet recruitingAutoimmune hepatitis makes a child's immune system attack their liver. Researchers at Assiut University Children's Hospital want to know how many children with this liver condition also develop thyroid disorders such as Hashimoto thyroiditis or Graves' disease. The team will test…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Eye damage in Graves' disease: can early clues predict who is at risk?
Knowledge-focused Not yet recruitingResearchers at the University of Copenhagen are studying why some people with newly diagnosed Graves' disease develop thyroid eye disease while others do not. The study follows about 430 participants for one year, collecting eye exams, blood and tear samples, and symptom question…
Sponsor: University of Copenhagen • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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Thyroid surgery under the microscope: what 3,000 real operations reveal
Knowledge-focused Not yet recruitingResearchers at a Moscow medical center are studying the quality and outcomes of thyroid surgery using real-world clinical data. The study follows patients who had thyroid operations for benign or malignant disease, tracking complications, cancer results, and long-term outcomes. B…
Sponsor: Pirogov Russian National Research Medical University • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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Iodine pills for moms may sharpen baby brains, new study hopes to prove
Knowledge-focused Not yet recruitingThis study tests whether giving breastfeeding mothers a daily iodine-containing multivitamin for 6 months helps their babies' brains and thyroid health. Researchers will compare babies' brain activity and development between moms who get the supplement and those who receive stand…
Phase 4 • Sponsor: Brown University • Aim: Knowledge-focused
Last updated Sep 11, 2026 00:00 UTC