Gastric intestinal metaplasia

This trial tests whether Weifuchun tablets can reverse gastric intestinal metaplasia, a condition where stomach lining cells change and may raise cancer risk. Adults without H. pylori infection will take Weifuchun or folic acid daily for six months, with regular checkups. The stu…

This study tests whether the drug pyrvinium can reverse gastric intestinal metaplasia, a condition that raises the risk of stomach cancer. Thirty-two adults with high-risk features will take pyrvinium or a placebo for 14 days. Researchers will compare biopsies before and after tr…

This study tests whether ursodeoxycholic acid, a bile acid medication, can reverse gastric intestinal metaplasia—a condition where the stomach lining changes and raises cancer risk. Researchers will give 196 adults without H. pylori infection either the drug or a placebo for 6 mo…

This study tests whether an artificial intelligence (AI) system can help doctors more accurately score a stomach condition called gastric intestinal metaplasia, which can lead to cancer. Eight endoscopists will review videos of stomach exams, some with AI help and some without, t…

This study tests an artificial intelligence system designed to automatically score precancerous changes in the stomach lining during endoscopy. Researchers will compare the AI's scores to those of expert doctors in 3,000 participants aged 40-75. The goal is to see if the AI can r…

This study investigates whether certain Helicobacter bacteria other than H. pylori are present in people with various stomach conditions, including chronic gastritis, precancerous changes, and gastric cancer. Researchers will analyze biopsy samples from about 150 patients to meas…

This study is investigating whether exposure to microplastics is linked to the development of stomach cancer and its early stages. Researchers will ask 450 people with different stomach conditions to fill out a detailed questionnaire about their possible exposure to microplastics…

This study looks at how common Helicobacter pylori (a stomach germ linked to cancer) is in adults without stomach symptoms who are already getting a screening colonoscopy. About 1,000 participants will also have a stomach exam (gastroscopy) during the same visit, with small tissu…

This study is building a registry of 3,200 people with early changes in the stomach lining that can lead to gastric cancer. Researchers will collect information on lifestyle, diet, and other risk factors through questionnaires. The goal is to better understand why some people dev…

This study follows 600 people at higher risk for stomach cancer to track precancerous changes in the stomach lining. Researchers collect tissue, blood, and saliva samples during routine endoscopies. The goal is to understand why some people's stomach changes progress to cancer wh…