Functional hypothalamic amenorrhea
MONDO:1060210A form of secondary amenorrhea caused by suppression of the hypothalamic-pituitary-ovarian axis without identifiable organic pathology, typically associated with energy deficiency, excessive exercise, psychological stress, or low body weight.
14 clinical trials for this condition and its sub-types, 14 tagged with Functional hypothalamic amenorrhea itself.
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Could a natural hormone restore ovulation in women with hypothalamic amenorrhea?
Disease control CompletedThis early study tested whether a naturally occurring hormone called kisspeptin can stimulate reproductive hormones and help women with hypothalamic amenorrhea (a condition where periods stop due to low hormone levels) release eggs. Thirteen women received pulsatile injections of…
Phase 1 • Sponsor: Stephanie B. Seminara, MD • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Fat tissue talks to the ovaries: scientists probe the hidden link
Knowledge-focused CompletedResearchers want to know whether the amount, location, and behavior of body fat contribute to two hormone conditions in women: hypothalamic amenorrhea, where menstrual periods stop, and polycystic ovary syndrome (PCOS). The study enrolls 50 women across five groups, including ath…
Sponsor: Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Study reveals how cutting calories disrupts Women's periods
Knowledge-focused CompletedThis study looked at how diet and exercise changes affect hormones and menstrual cycles in healthy women aged 18-28. Participants followed special diets and exercise programs while researchers measured hormone levels. The goal was to better understand a condition called functiona…
Sponsor: National Institute of Environmental Health Sciences (NIEHS) • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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Teen bone health under the microscope: new study looks at why some girls develop weak bones
Knowledge-focused CompletedThis completed study looked back at the medical records of 74 adolescent girls aged 12 to 21 who had bone density scans. Researchers wanted to find out which girls are most at risk for low bone density (osteopenia or osteoporosis), especially those with missed periods or other gy…
Sponsor: Bagcilar Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:13 UTC