Female reproductive organ cancer
MONDO:0001416A primary or metastatic malignant neoplasm involving the female reproductive system. Representative examples include endometrial carcinoma, cervical carcinoma, ovarian carcinoma, uterine corpus leiomyosarcoma, adenosarcoma, malignant mixed mesodermal (mullerian) tumor, and gestational choriocarcinoma.
Also known as: cancer of female reproductive organ, female reproductive cancer, female reproductive organ cancer, gynecologic cancer, malignant female reproductive organ neoplasm, malignant female reproductive system neoplasm, malignant female reproductive system tumor, malignant female reproductive system tumour
4802 clinical trials for this condition and its sub-types, 245 tagged with Female reproductive organ cancer itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Female reproductive organ cancer
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Uterine cancer 96 trials · 1,264 incl. sub-types
7 sub-types
- Cervical cancer 576 trials · 700 incl. sub-types Sub-types →
- Endometrial cancer 458 trials · 650 incl. sub-types Sub-types →
- Uterine carcinoma 3 trials · 614 incl. sub-types Sub-types →
- Uterine corpus cancer 33 trials · 85 incl. sub-types Sub-types →
- Uterine carcinosarcoma 23 trials · 32 incl. sub-types Sub-types →
- Placenta cancer 0 trials · 1 incl. sub-types Sub-types →
- Uterine adnexa cancer 0 trials Sub-types →
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Ovarian cancer 1,004 trials · 1,200 incl. sub-types
11 sub-types
- Malignant epithelial tumor of ovary 8 trials · 656 incl. sub-types Sub-types →
- Malignant non-epithelial tumor of ovary 1 trial · 9 incl. sub-types Sub-types →
- Familial ovarian cancer 1 trial · 8 incl. sub-types Sub-types →
- Ovarian neuroendocrine neoplasm 0 trials · 2 incl. sub-types Sub-types →
- Ovarian sarcoma 0 trials · 2 incl. sub-types Sub-types →
- Malignant ovarian cyst 1 trial
- Ovarian Wilms tumor 0 trials
- Ovarian adenosarcoma 0 trials
- Ovarian endometrioid adenocarcinofibroma 0 trials
- Ovarian lymphoma 0 trials
- Ovarian malignant mesothelioma 0 trials
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Fallopian tube cancer 298 trials · 408 incl. sub-types
4 sub-types
- Fallopian tube carcinoma 126 trials · 182 incl. sub-types Sub-types →
- Cancer of isthmus of fallopian tube 0 trials
- Fallopian tube adenosarcoma 0 trials
- Fallopian tube leiomyosarcoma 0 trials
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Endometrioid adenocarcinoma 13 trials · 146 incl. sub-types
6 sub-types
- Ovarian endometrioid adenocarcinoma 78 trials Sub-types →
- Endometrial endometrioid adenocarcinoma 56 trials Sub-types →
- Fallopian tube endometrioid adenocarcinoma 30 trials
- Stage I endometrioid carcinoma 16 trials
- Stage II endometrioid carcinoma 2 trials
- Cervical endometrioid adenocarcinoma 0 trials Sub-types →
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Vulva cancer 88 trials · 102 incl. sub-types
8 sub-types
- Vulvar carcinoma 24 trials · 45 incl. sub-types Sub-types →
- Vulvar melanoma 3 trials
- Clitoris cancer 0 trials Sub-types →
- Labia minora cancer 0 trials Sub-types →
- Labium majus cancer 0 trials Sub-types →
- Mixed germ cell tumor of vulva 0 trials
- Paraurethral gland cancer 0 trials Sub-types →
- Vulva sarcoma 0 trials Sub-types →
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Vaginal cancer 53 trials · 60 incl. sub-types
5 sub-types
- Vaginal carcinoma 12 trials · 22 incl. sub-types Sub-types →
- Malignant vaginal mixed epithelial and mesenchymal neoplasm 0 trials Sub-types →
- Vagina sarcoma 0 trials Sub-types →
- Vaginal adenosarcoma 0 trials
- Vaginal germ cell malignant tumor 0 trials Sub-types →
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Adenosarcoma 0 trials · 2 incl. sub-types
5 sub-types
- Cervical adenosarcoma 1 trial Sub-types →
- Uterine corpus adenosarcoma 1 trial
- Fallopian tube adenosarcoma 0 trials
- Ovarian adenosarcoma 0 trials
- Vaginal adenosarcoma 0 trials
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Gestational choriocarcinoma 0 trials · 1 incl. sub-types
4 sub-types
- Placental choriocarcinoma 1 trial
- Fallopian tube gestational choriocarcinoma 0 trials
- Gestational ovarian choriocarcinoma 0 trials
- Uterine corpus choriocarcinoma 0 trials
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Adenocarcinofibroma 0 trials
3 sub-types
- Ovarian endometrioid adenocarcinofibroma 0 trials
- Ovarian mucinous adenocarcinofibroma 0 trials
- Uterine corpus adenocarcinofibroma 0 trials
Most studied deeper sub-types
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Supercharged immune cells take on cancer in new trial
Disease control Stopped earlyThis study tests whether specially engineered immune cells (EIE) can safely fight cancer. Researchers take a patient's own immune cells, modify them to target tumor-related markers, and infuse them back. The trial involves 100 people with various cancers whose tumors show specifi…
Phase 1/2 • Sponsor: Shenzhen Geno-Immune Medical Institute • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Quitting before the knife: which Stop-Smoking aid works best for cancer patients?
Disease control Stopped earlyThis trial explores whether adding counseling, cognitive behavioural therapy, or hypnotherapy to nicotine replacement therapy can help cancer patients quit smoking before their surgery. The study includes adults with breast, digestive, gynecologic cancer, or melanoma who smoke da…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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New cocktail of cancer drugs tested in desperate cases
Disease control Stopped earlyThis early-phase trial tested combinations of the drugs bevacizumab and temsirolimus, sometimes with valproic acid or cetuximab, in 154 people with advanced cancers or certain non-cancerous but progressive diseases. The main goal was to find safe doses and look for any signs that…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Experimental TIL therapy for advanced gynecological tumors shows early promise but study halted
Disease control Stopped earlyThis early study tested a new treatment called GT201 for people with advanced gynecological tumors, like advanced cervical cancer. The treatment uses a patient's own immune cells (tumor-infiltrating lymphocytes) to fight the cancer. The study was terminated early after enrolling …
Sponsor: Grit Biotechnology • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Experimental TIL therapy tested in one patient for advanced gynecological tumors
Disease control Stopped earlyThis early-phase study tested an experimental cell therapy called GT201, made from a patient's own immune cells, for advanced gynecological tumors. Only one person took part before the study was stopped early. The goal was to check safety and see if the treatment could shrink tum…
Early phase 1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Immune cell therapy tested for tough childhood cancers
Disease control Stopped earlyThis early-phase study tested a treatment using donated natural killer (NK) cells from cord blood, combined with chemotherapy, for children and young adults with solid tumors that returned or didn't respond to standard care. The goal was to find the safest dose and check for side…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Quit smoking before surgery to cut complications, study finds
Disease control Stopped earlyThis study looked at whether a structured smoking cessation program starting four weeks before surgery could reduce complications in smokers undergoing intermediate to high-risk operations. Researchers planned to enroll 251 adult smokers scheduled for surgeries like abdominal, th…
Sponsor: Luzerner Kantonsspital • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Cancer-Fighting super cells tested in solid tumors – study halted early
Disease control Stopped earlyThis study tested a personalized treatment where a patient's own immune cells were modified in a lab to recognize and attack unique markers on their cancer cells. It involved 8 people with advanced solid tumors like lung, pancreatic, or ovarian cancer that had not responded to st…
Phase 1/2 • Sponsor: Alaunos Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Skin-Saving paste for cancer radiation falls short in tiny trial
Prevention Stopped earlyThis study tested whether Alkagin paste could prevent skin damage in patients receiving radiation for anal, rectal, or gynecological cancers. Only 2 people enrolled before the trial was stopped early. Because of this, we cannot draw any reliable conclusions about the paste's effe…
Phase 2 • Sponsor: Sir Mortimer B. Davis - Jewish General Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:32 UTC
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Could a High-Tech headband clear the fog of chemo brain?
Symptom relief Stopped earlyThis study tests whether a headband with special semiconductors can help with memory and thinking problems (often called 'chemo brain') in people who have had breast or gynecologic cancer. About 50 participants will wear either the active headband or a placebo version for 18 hour…
Phase 2 • Sponsor: University of Utah • Aim: Symptom relief
Last updated Aug 19, 2026 00:00 UTC
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Mouthwash may fight Chemo's bitter side effect
Symptom relief Stopped earlyThis pilot study tested a mouthwash made with homoeriodictyol sodium to reduce bitter taste caused by chemotherapy in women with gynecologic cancers. The study aimed to see if the mouthwash could improve taste and food intake. Only 15 participants were enrolled, and the trial was…
Sponsor: Christoph Grimm • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Simple 5-Minute exam may spot hidden pelvic damage after cancer radiation
Knowledge-focused Stopped earlyThis study aimed to find a better way to detect pelvic floor problems caused by radiation treatment for gynecologic cancer. Researchers tested a 5-minute single-digit pelvic exam on 22 patients undergoing chemoradiotherapy for cervical cancer. The goal was to see if this exam cou…
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC