Esophageal disorder
MONDO:0003749A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.
Also known as: disease of esophagus, disease of oesophagus, disease or disorder of esophagus, disease or disorder of oesophagus, disorder of esophagus, disorder of oesophagus, esophageal disorder, esophagus disease
1222 clinical trials for this condition and its sub-types, 20 tagged with Esophageal disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Esophageal disorder
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Neoplasm of esophagus 34 trials · 796 incl. sub-types
5 sub-types
- Esophageal cancer 408 trials · 787 incl. sub-types Sub-types →
- Benign neoplasm of esophagus 3 trials Sub-types →
- Esophageal neuroendocrine tumor 1 trial · 3 incl. sub-types Sub-types →
- Esophageal granular cell tumor 0 trials
- Neurofibroma of the esophagus 0 trials
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Gastroesophageal reflux disease 217 trials
1 sub-type
- Duodenogastric reflux 0 trials
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Esophagitis 22 trials · 102 incl. sub-types
6 sub-types
- Eosinophilic esophagitis 67 trials Sub-types →
- Peptic esophagitis 24 trials
- Crohn disease of the esophagus 1 trial
- Bacterial esophagitis 0 trials
- Fungal esophagitis 0 trials Sub-types →
- Viral esophagitis 0 trials
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Barrett esophagus 73 trials
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Esophageal varices 34 trials · 55 incl. sub-types
2 sub-types
- Esophageal varices with bleeding 29 trials
- Esophageal varices without bleeding 0 trials
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Achalasia 35 trials · 43 incl. sub-types
2 sub-types
- Idiopathic achalasia 12 trials
- Achalasia, familial esophageal 0 trials
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Esophageal ulcer 1 trial · 25 incl. sub-types
1 sub-type
- Peptic esophagitis 24 trials
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Dyskinesia of esophagus 20 trials
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Esophageal atresia 12 trials
1 sub-type
- Arroyo Garcia Cimadevilla syndrome 0 trials
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Isolated tracheo-esophageal fistula 2 trials
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Congenital esophageal stenosis 1 trial
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Esophageal diverticulosis 1 trial
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Esophageal leukoplakia 1 trial
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Laryngotracheoesophageal cleft 1 trial
6 sub-types
- Cleft larynx, posterior 0 trials
- Laryngotracheoesophageal cleft type 0 0 trials
- Laryngotracheoesophageal cleft type 1 0 trials
- Laryngotracheoesophageal cleft type 2 0 trials
- Laryngotracheoesophageal cleft type 3 0 trials
- Laryngotracheoesophageal cleft type 4 0 trials
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Congenital esophageal diverticulum 0 trials
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Esophageal duplication cyst 0 trials
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Esophageal tuberculosis 0 trials
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Megaesophagus 0 trials
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Tubular duplication of the esophagus 0 trials
Most studied deeper sub-types
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New drug shows promise for Long-Term control of esophagus inflammation
Disease control CompletedThis study looks at the long-term safety of a drug called CC-93538 (cendakimab) for people with eosinophilic esophagitis, a condition that causes inflammation in the esophagus. It enrolled 367 adults and teens who had already taken part in earlier studies of the same drug. The ma…
Phase 3 • Sponsor: Celgene • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New hope for preventing Post-Surgery confusion in seniors
Symptom relief CompletedThis study tested whether giving a small amount of s-ketamine during chest surgery could reduce the risk of postoperative delirium (sudden confusion) in patients aged 60 and older. Over 500 participants were randomly assigned to receive either s-ketamine or another drug (dexmedet…
Early phase 1 • Sponsor: Affiliated Cancer Hospital & Institute of Guangzhou Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Blood tests may replace scopes for EoE diagnosis
Knowledge-focused CompletedThis study enrolled 800 adults undergoing upper endoscopy to find risk factors and blood markers that could help diagnose and monitor eosinophilic esophagitis (EoE), a chronic allergic condition of the esophagus. Researchers compared people with and without EoE, collecting blood,…
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Massive study sheds light on esophageal cancer surgery outcomes
Knowledge-focused CompletedThis study analyzed data from nearly 3,000 patients who had surgery for esophageal cancer between 2000 and 2010. Researchers looked at factors like patient health, treatment approach, and surgical technique to see what influences cancer recurrence and survival. The goal is to bet…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC