Endocrine system disorder
MONDO:0005151A disease involving the endocrine system.
Also known as: disease of endocrine system, disease or disorder of endocrine system, disorder of endocrine system, endocrine disease, endocrine disorder, endocrine system disease, endocrine system disease or disorder, endocrine system disorder
12512 clinical trials for this condition and its sub-types, 78 tagged with Endocrine system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Endocrine system disorder
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Pancreas disorder 44 trials · 5,601 incl. sub-types
14 sub-types
- Endocrine pancreas disorder 1 trial · 3,937 incl. sub-types Sub-types →
- Pancreatic neoplasm 929 trials · 1,579 incl. sub-types Sub-types →
- Pancreatitis 120 trials · 203 incl. sub-types Sub-types →
- Exocrine pancreatic insufficiency 30 trials Sub-types →
- Recurrent acute pancreatitis 19 trials
- Accessory pancreas 0 trials
- Acinar cystic transformation of the pancreas 0 trials
- Annular pancreas 0 trials
- Congenital pancreatic cyst 0 trials
- Follicular cholangitis and pancreatitis 0 trials
- Lymphoepithelial cyst of the pancreas 0 trials
- Pancreatic mucinous ductal ectasia 0 trials
- Pancreatic steatorrhea 0 trials
- Pancreatic triacylglycerol lipase deficiency 0 trials Sub-types →
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Liver disorder 324 trials · 3,621 incl. sub-types
32 sub-types
- Liver and intrahepatic bile duct neoplasm 78 trials · 1,752 incl. sub-types Sub-types →
- Hepatitis 51 trials · 734 incl. sub-types Sub-types →
- Fatty liver disease 154 trials · 617 incl. sub-types Sub-types →
- Cirrhosis of liver 522 trials · 602 incl. sub-types Sub-types →
- Liver failure 71 trials · 199 incl. sub-types Sub-types →
- Hepatic vascular disorder 1 trial · 116 incl. sub-types Sub-types →
- Fibrotic liver disease 96 trials
- Alcoholic liver disease 44 trials · 88 incl. sub-types Sub-types →
- Drug-induced liver injury 22 trials · 24 incl. sub-types Sub-types →
- Hepatic porphyria 4 trials · 23 incl. sub-types Sub-types →
- Transient familial neonatal hyperbilirubinemia 18 trials
- Familial intrahepatic cholestasis 1 trial · 17 incl. sub-types Sub-types →
- Hepatorenal syndrome 13 trials
- Bile duct cyst 10 trials
- Liver abscess (disease) 4 trials
- Autosomal dominant polycystic liver disease 3 trials Sub-types →
- Cystic fibrosis-related liver disease 3 trials
- Intestinal failure–associated liver disease 3 trials
- Nodular regenerative hyperplasia of the liver 3 trials
- Glycogen storage disease due to liver phosphorylase kinase deficiency 0 trials · 2 incl. sub-types Sub-types →
- Aagenaes syndrome 1 trial
- Early-onset familial noncirrhotic portal hypertension 0 trials
- Hepatoportal sclerosis 0 trials
- Hepatopulmonary syndrome 0 trials
- Hyperbiliverdinemia 0 trials
- Idiopathic copper-associated cirrhosis 0 trials
- Liver disease, severe congenital 0 trials
- Membranous obstruction of inferior vena cava 0 trials
- Perinatal jaundice due to hepatocellular damage 0 trials
- Polycystic echinococcosis 0 trials
- Primitive portal vein thrombosis 0 trials
- Transient infantile hypertriglyceridemia and hepatosteatosis 0 trials
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Endocrine gland neoplasm 8 trials · 3,341 incl. sub-types
14 sub-types
- Malignant endocrine neoplasm 17 trials · 2,932 incl. sub-types Sub-types →
- Liver and intrahepatic bile duct neoplasm 78 trials · 1,752 incl. sub-types Sub-types →
- Neuroendocrine neoplasm 181 trials · 985 incl. sub-types Sub-types →
- Thyroid tumor 36 trials · 366 incl. sub-types Sub-types →
- Thymus neoplasm 5 trials · 240 incl. sub-types Sub-types →
- Adrenal gland neoplasm 13 trials · 151 incl. sub-types Sub-types →
- Pituitary tumor 23 trials · 83 incl. sub-types Sub-types →
- Benign endocrine neoplasm 0 trials · 60 incl. sub-types Sub-types →
- Tumor of parathyroid gland 3 trials · 46 incl. sub-types Sub-types →
- Functioning endocrine neoplasm 0 trials · 38 incl. sub-types Sub-types →
- Pineal body neoplasm 4 trials · 22 incl. sub-types Sub-types →
- Non-functioning endocrine neoplasm 0 trials · 16 incl. sub-types Sub-types →
- Granulosa cell tumor 2 trials · 6 incl. sub-types Sub-types →
- Familial tumoral calcinosis 1 trial Sub-types →
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Gonadal disorder 3 trials · 1,639 incl. sub-types
6 sub-types
- Ovarian disorder 10 trials · 1,391 incl. sub-types Sub-types →
- Hypogonadism 47 trials · 164 incl. sub-types Sub-types →
- Testicular disorder 2 trials · 111 incl. sub-types Sub-types →
- Disorder of sexual differentiation 9 trials · 55 incl. sub-types Sub-types →
- Precocious puberty 18 trials · 19 incl. sub-types Sub-types →
- Gonadoblastoma 0 trials Sub-types →
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Autoimmune disorder of endocrine system 1 trial · 929 incl. sub-types
13 sub-types
- Type 1 diabetes mellitus 819 trials · 820 incl. sub-types Sub-types →
- Autoimmune thyroid disease 8 trials · 62 incl. sub-types Sub-types →
- Autoimmune hepatitis 30 trials · 31 incl. sub-types Sub-types →
- Autoimmune polyendocrinopathy 3 trials · 11 incl. sub-types Sub-types →
- Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome 10 trials
- Autoimmune hypoparathyroidism 0 trials · 8 incl. sub-types Sub-types →
- Autoimmune pancreatitis 3 trials Sub-types →
- Autoimmune primary ovarian failure 1 trial
- IgG4-related sclerosing cholangitis 0 trials
- Autoimmune enteropathy and endocrinopathy - susceptibility to chronic infections syndrome 0 trials
- Autoimmune oophoritis 0 trials
- Insulin autoimmune syndrome 0 trials
- Primary hypophysitis 0 trials Sub-types →
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Thyroid gland disorder 96 trials · 538 incl. sub-types
12 sub-types
- Thyroid tumor 36 trials · 366 incl. sub-types Sub-types →
- Goiter 12 trials · 102 incl. sub-types Sub-types →
- Hyperthyroidism 27 trials · 70 incl. sub-types Sub-types →
- Thyroiditis 1 trial · 62 incl. sub-types Sub-types →
- Hypothyroidism 48 trials · 60 incl. sub-types Sub-types →
- Inherited thyroid metabolism disease 0 trials · 8 incl. sub-types Sub-types →
- C-cell hyperplasia 0 trials
- Atrophy of thyroid 0 trials
- Euthyroid sick syndrome 0 trials
- Hyperthyroxinemia 0 trials Sub-types →
- Thyrocalcitonin secretion disease 0 trials
- Thyroid malformation 0 trials
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Adrenal gland disorder 9 trials · 354 incl. sub-types
18 sub-types
- Adrenal cortex disorder 0 trials · 185 incl. sub-types Sub-types →
- Adrenal gland neoplasm 13 trials · 151 incl. sub-types Sub-types →
- Adrenogenital syndrome 0 trials · 41 incl. sub-types Sub-types →
- Pituitary dwarfism 40 trials Sub-types →
- Endogenous Cushing syndrome 3 trials · 38 incl. sub-types Sub-types →
- Adrenoleukodystrophy 19 trials · 20 incl. sub-types Sub-types →
- Ectopic ACTH secretion syndrome 15 trials
- Autoimmune polyendocrine syndrome type 1 8 trials
- Primary pigmented nodular adrenocortical disease 2 trials Sub-types →
- Congenital adrenal insufficiency with 46, XY sex reversal OR 46,XY disorder of sex development-adrenal insufficiency due to CYP11A1 deficiency 1 trial
- Apparent mineralocorticoid excess 1 trial
- Hypoaldosteronism disease 1 trial Sub-types →
- Adrenal medullary hyperplasia 0 trials
- Adrenomyodystrophy 0 trials
- Corticosteroid-binding globulin deficiency 0 trials
- Isolated micronodular adrenocortical disease 0 trials
- Medulloadrenal hyperfunction 0 trials
- Pseudoleprechaunism syndrome, Patterson type 0 trials
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Thymus gland disorder 1 trial · 240 incl. sub-types
3 sub-types
- Thymus neoplasm 5 trials · 240 incl. sub-types Sub-types →
- Ectopic thymus 0 trials
- Thymic dysplasia 0 trials
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Polycystic ovary syndrome 201 trials
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Hereditary endocrine growth disease 26 trials · 196 incl. sub-types
8 sub-types
- Non-acquired pituitary hormone deficiency 0 trials · 85 incl. sub-types Sub-types →
- Inherited primary ovarian failure 2 trials · 48 incl. sub-types Sub-types →
- Congenital adrenal hyperplasia 36 trials · 38 incl. sub-types Sub-types →
- Growth hormone insensitivity syndrome 0 trials · 6 incl. sub-types Sub-types →
- Permanent congenital hypothyroidism 1 trial · 3 incl. sub-types Sub-types →
- Zerres Rietschel Majewski syndrome 0 trials
- Cataract-growth hormone deficiency-sensory neuropathy-sensorineural hearing loss-skeletal dysplasia syndrome 0 trials
- Microdontia hypodontia short stature 0 trials
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Pituitary gland disorder 18 trials · 175 incl. sub-types
9 sub-types
- Pituitary tumor 23 trials · 83 incl. sub-types Sub-types →
- Anterior pituitary gland disorder 1 trial · 60 incl. sub-types Sub-types →
- Hypopituitarism 5 trials · 46 incl. sub-types Sub-types →
- Neurohypophyseal diabetes insipidus 9 trials
- Inappropriate ADH syndrome 5 trials
- Hypophysitis 2 trials Sub-types →
- Necrosis of pituitary 0 trials · 1 incl. sub-types Sub-types →
- Empty sella syndrome 0 trials
- Pituitary hypoplasia 0 trials
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Non-neoplastic bile duct disorder 0 trials · 172 incl. sub-types
5 sub-types
- Cholangitis 17 trials · 139 incl. sub-types Sub-types →
- Biliary atresia 24 trials Sub-types →
- Obstructive jaundice 11 trials
- Caroli disease 1 trial
- Extrahepatic cholestasis 0 trials Sub-types →
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Parathyroid gland disorder 14 trials · 164 incl. sub-types
4 sub-types
- Hyperparathyroidism 8 trials · 89 incl. sub-types Sub-types →
- Hypoparathyroidism 46 trials · 66 incl. sub-types Sub-types →
- Tumor of parathyroid gland 3 trials · 46 incl. sub-types Sub-types →
- Parathyroid hyperplasia 0 trials
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Beta thalassemia 73 trials · 99 incl. sub-types
3 sub-types
- Beta-thalassemia HBB/LCRB 2 trials · 57 incl. sub-types Sub-types →
- Dominant beta-thalassemia 0 trials
- Thalassemia, beta+, silent allele 0 trials
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Pituitary deficiency 0 trials · 97 incl. sub-types
5 sub-types
- Non-acquired pituitary hormone deficiency 0 trials · 85 incl. sub-types Sub-types →
- Central diabetes insipidus 5 trials · 12 incl. sub-types Sub-types →
- Acquired pituitary hormone deficiency 0 trials · 1 incl. sub-types Sub-types →
- Pituitary deficiency due to Rathke's pouch cysts 0 trials
- Pituitary deficiency due to empty sella turcica syndrome 0 trials
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Polyendocrinopathy 0 trials · 81 incl. sub-types
7 sub-types
- Multiple polyglandular tumor 0 trials · 62 incl. sub-types Sub-types →
- Autoimmune polyendocrinopathy 3 trials · 11 incl. sub-types Sub-types →
- Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome 10 trials
- Bangstad syndrome 0 trials
- Autoimmune enteropathy and endocrinopathy - susceptibility to chronic infections syndrome 0 trials
- Neuroectodermal-endocrine syndrome 0 trials
- Retinohepatoendocrinologic syndrome 0 trials
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Neuroendocrine disorder 0 trials · 42 incl. sub-types
4 sub-types
- Pineal body neoplasm 4 trials · 22 incl. sub-types Sub-types →
- Central diabetes insipidus 5 trials · 12 incl. sub-types Sub-types →
- Cyclic vomiting syndrome 8 trials
- Posterior pituitary gland neoplasm 0 trials Sub-types →
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Hyperinsulinemic hypoglycemia 2 trials · 14 incl. sub-types
5 sub-types
- Familial hyperinsulinism 9 trials · 12 incl. sub-types Sub-types →
- Hyperinsulinemic hypoglycemia, familial, 1 1 trial Sub-types →
- Hyperinsulinemic hypoglycemia with polycystic kidney disease 0 trials
- Hyperinsulinemic hypoglycemia, familial, 8 0 trials
- Insulin autoimmune syndrome 0 trials
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Parneoplastic endocrine syndrome 0 trials · 11 incl. sub-types
2 sub-types
- POEMS syndrome 8 trials
- Oncogenic osteomalacia 3 trials
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Inherited obesity 8 trials · 9 incl. sub-types
7 sub-types
- Obesity due to pro-opiomelanocortin deficiency 2 trials
- Obesity due to congenital leptin deficiency 1 trial
- Obesity due to leptin receptor gene deficiency 1 trial
- Obesity due to prohormone convertase I deficiency 1 trial
- Obesity due to CEP19 deficiency 0 trials
- Obesity due to SIM1 deficiency 0 trials
- Obesity due to melanocortin 4 receptor deficiency 0 trials
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Acquired hypothalamic obesity 7 trials
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Disorder of GNAS inactivation 0 trials · 7 incl. sub-types
5 sub-types
- Pseudohypoparathyroidism type 1A 7 trials
- Pseudopseudohypoparathyroidism 2 trials
- Progressive osseous heteroplasia 0 trials
- Pseudohypoparathyroidism type 1B 0 trials
- Pseudohypoparathyroidism type 1C 0 trials
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Disorders of vitamin D metabolism 0 trials · 3 incl. sub-types
1 sub-type
- Hypocalcemic rickets 0 trials · 3 incl. sub-types Sub-types →
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NKX2-1 related choreoathetosis and congenital hypothyroidism with or without pulmonary dysfunction 0 trials · 1 incl. sub-types
3 sub-types
- Thyroid cancer, nonmedullary, 1 1 trial
- Brain-lung-thyroid syndrome 0 trials
- Hereditary progressive chorea without dementia 0 trials
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Familial hypocalciuric hypercalcemia 0 trials · 1 incl. sub-types
3 sub-types
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17,20-lyase deficiency, isolated 0 trials
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Bamforth-Lazarus syndrome 0 trials
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Leydig cell hypoplasia 0 trials
2 sub-types
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Wolfram-like syndrome 0 trials
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Campomelic dysplasia 0 trials
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Diencephalic syndrome 0 trials
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Duplication of the pituitary gland 0 trials
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Endocrine tuberculosis 0 trials
1 sub-type
- Hepatic tuberculosis 0 trials
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Estrogen resistance syndrome 0 trials
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Genito-palato-cardiac syndrome 0 trials
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Neonatal iodine exposure 0 trials
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Thyroid hormone metabolism, abnormal 0 trials
3 sub-types
- Thyroid hormone metabolism, abnormal 1 0 trials
- Thyroid hormone metabolism, abnormal, 2 0 trials
- Thyroid hormone metabolism, abnormal, 3 0 trials
Most studied deeper sub-types
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Testosterone may rebuild strength after spinal cord injury — trial puts it to the test
Disease control Not yet recruitingThis trial tests whether testosterone therapy can help men with spinal cord injury who have low testosterone and difficulty walking. The goal is to see if it increases muscle and bone in the legs, reduces body fat, and improves strength. Some participants also receive finasteride…
Phase 2/3 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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A breath sniff could one day screen for lung cancer and more
Diagnosis Not yet recruitingResearchers are testing whether an electronic nose that analyzes exhaled breath can serve as a noninvasive prescreening tool for several diseases at once. The study plans to enroll up to 20,000 adults and will first standardize the breath-sampling procedure, then evaluate how wel…
Sponsor: The First Affiliated Hospital of Guangzhou Medical University • Aim: Diagnosis
Last updated Sep 06, 2026 00:00 UTC
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Ancient remedy meets modern prebiotic: a new hope for Shift-Worker fatigue?
Symptom relief Not yet recruitingThis trial is testing whether a combination of Bao Yuan Tang, a traditional Chinese medicine extract, and galactooligosaccharides, a type of prebiotic, can improve sleep quality, reduce fatigue, and support better metabolism in female nurses who work night shifts. The study will …
Sponsor: Hepatopancreatobiliary Surgery Institute of Gansu Province • Aim: Symptom relief
Last updated Aug 21, 2026 00:00 UTC
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Does feeling stigmatized worsen life quality for men with low testosterone?
Knowledge-focused Not yet recruitingThis study looks at how anticipated stigma and illness identity affect quality of life in men with hypogonadism (low testosterone). It compares these men to those with other chronic endocrine conditions like diabetes, hypothyroidism, or hypertension. The goal is to see if these p…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Childhood head trauma may cause hidden hormone issues years later
Knowledge-focused Not yet recruitingThis study checks on children who had a moderate to severe head injury years ago to see if they have any lasting hormone or growth problems. Researchers will call participants for a 15-minute interview to measure their height and ask about symptoms. The goal is to learn how commo…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Massive diabetes registry aims to unlock secrets of metabolic disease
Knowledge-focused Not yet recruitingThis 10-year observational study will follow 10,000 adults with diabetes, metabolic disorders, and related conditions like high blood pressure and fatty liver disease. Researchers will collect routine medical data to identify markers of disease severity and activity. The goal is …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Million-Person study links ancient chinese medicine to modern disease prevention
Knowledge-focused Not yet recruitingThis study will follow one million adults in China aged 30 to 74 for up to 10 years. Researchers will collect health data and Traditional Chinese Medicine (TCM) body type information to see how they relate to chronic diseases like heart disease, diabetes, and cancer. The goal is …
Sponsor: Huazhong University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC