Disease related to transplantation

This study compares high-dose and standard-dose flu vaccines in 396 adults who received a kidney, heart, or liver transplant within the past year. The goal is to see if a higher dose or two doses provide better protection against the flu. Results will help improve vaccine recomme…

This study looked at whether adding the drug cidofovir to usual care helps people who develop painful bladder bleeding from the BK virus after a stem cell transplant. About 27 participants received either cidofovir or standard supportive care. The goal was to see if symptoms impr…

This study compares a high-dose flu vaccine to the standard dose in 270 lung transplant recipients who are 1 to 35 months post-transplant. The goal is to see if the high-dose vaccine triggers a stronger immune response and provides better protection against influenza. Participant…

This small pilot study is testing whether curcumin, the active ingredient in turmeric, can improve blood vessel health and thinking skills in kidney transplant recipients. Fourteen participants will take either curcumin or a placebo for 12 months. The goal is to see if this safe,…

This study looks at whether switching to a plant-based diet can improve heart health and reduce inflammation in people who have had a kidney transplant. Twenty-five participants who are at least three months post-transplant will follow a plant-based diet for 16 weeks after a two-…

This early-phase trial tests the safety of combining donor anti-inflammatory Treg cells with low-dose Interleukin-2 (IL-2) for people with chronic graft-versus-host disease (cGVHD) that hasn't responded to steroids. cGVHD is a complication after a stem cell or bone marrow transpl…

This study looks at why people who have had an organ transplant are more likely to get cancer. Researchers will combine existing health records from over 85,000 transplant patients in England to track cancer cases and deaths. The goal is to better understand risks and improve car…

This study is testing a new method to monitor the immune system after a liver transplant. The goal is to see if a personalized approach can help doctors adjust immunosuppression drugs more accurately, reducing the risk of rejection or infection. Forty adult liver transplant recip…