Diaphragm disorder

This trial tests whether a newer ventilation method, called flow-controlled ventilation, keeps the lungs and diaphragm in better shape than the standard pressure-controlled method during elective heart bypass surgery. About 154 adults scheduled for on-pump coronary artery bypass …

This study tests a new way to measure diaphragm activity using ultrasound in patients on a breathing machine (ventilator). The goal is to see if this measurement can help doctors identify when the lungs are not fully emptying and adjust ventilator pressure accordingly. The study …

This study will compare two types of nerve blocks for pain relief after shoulder surgery. One is a standard block that can sometimes weaken breathing; the other is a newer block that may avoid that side effect. 120 adults having shoulder arthroscopy will be randomly assigned to o…

This study looks at whether a special breathing exercise (threshold inspiratory muscle training) can make the diaphragm thicker and move better in people with stable COPD. Fifteen participants aged 40-59 with moderate COPD will do the training. The goal is to see if this exercise…

Researchers at Radboud University Medical Center are studying whether the diaphragm, the main breathing muscle, enters a hibernation-like state in ICU patients who need a breathing machine. The study follows 112 adults on invasive mechanical ventilation for at least three days. S…

Researchers are studying whether repeated bedside ultrasound scans of the diaphragm can predict breathing failure in adults with septic shock. The study follows 120 patients in intensive care for up to 72 hours, measuring how far the diaphragm moves and how thick it is. The team …

This study looks at whether diaphragm ultrasound gives consistent results when performed by different anesthesiologists. Two doctors will each scan the diaphragm using three different methods, and their measurements will be compared to see which method is most reliable. The goal …

This study tests whether a new ultrasound-based index, called the Regional Diaphragmatic Synchrony Index (RDSI), can predict if patients on ventilators will succeed when their breathing tube is removed. Researchers will measure diaphragm movement and thickness in 110 adults durin…

This study compares two types of nerve blocks used during shoulder surgery to see which one causes less diaphragm paralysis (temporary trouble breathing). Sixty adults scheduled for shoulder surgery will receive either a standard interscalene block or a combination block. Researc…

This study checks if a special ultrasound technique (shear-wave elastography) can accurately measure diaphragm pressure without needles or tubes. Twelve healthy adults will perform breathing exercises while researchers compare ultrasound readings to standard pressure measurements…

This study looks at how long-term use of a BiPAP machine affects the diaphragm—the main breathing muscle—in people with advanced COPD. Researchers will use ultrasound to measure diaphragm thickness and movement over 6 weeks and 12 months in 30 patients. The goal is to learn wheth…