De Quervain disease
MONDO:0006721Stenosing tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons in the first dorsal wrist compartment. The presenting symptoms are usually pain and tenderness at the radial styloid. The cause is almost always related to overuse injury or is associated with rheumatoid arthritis.
Also known as: radial styloid tenosynovitis
28 clinical trials for this condition and its sub-types, 17 tagged with De Quervain disease itself.
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Simple hand exercises could ease 'Smartphone Thumb' pain
Symptom relief CompletedThis study tests whether combining two types of hand exercises—Mulligan's mobilization and tendon gliding—can improve hand function in smartphone users with De Quervain's tenosynovitis, a painful thumb condition. About 44 participants will be randomly assigned to either the exerc…
Sponsor: Riphah International University • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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Wrist pain showdown: injection or surgery for de Quervain's?
Symptom relief CompletedThis study compares two common treatments for De Quervain's tenosynovitis, a painful wrist condition: a single steroid injection versus a minor surgical release. Researchers will track pain levels in 100 adults over six months to see which approach offers better relief. The goal …
Sponsor: Rawalpindi Teaching Hospital, District Headquarter Hospital, Rawalpindi • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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Hand pain relief: which therapy works better for de Quervain's?
Symptom relief CompletedThis study tested two hands-on treatments for De Quervain's tenosynovitis, a painful wrist condition. 32 adults received either the Graston Technique (using a special tool) or Myofascial Release (gentle stretching) alongside standard physical therapy. Researchers measured pain an…
Sponsor: Elite College of Management Sciences, Gujranwala, Pakistan • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Simple exercises may soothe stubborn thumb pain without surgery
Symptom relief CompletedThis study tested whether a structured eccentric training program—exercises that lengthen the muscle under load—could reduce pain and improve hand function in 25 adults with de Quervain's tendinopathy who had not gotten better with other treatments. Participants did the exercises…
Sponsor: Dr. Lenti Katalin • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Steroid or painkiller shot: which works better for thumb tendonitis?
Symptom relief CompletedThis study tested whether a steroid injection (betamethasone) or a nonsteroidal anti-inflammatory injection (ketorolac) better relieves pain from DeQuervain's tenosynovitis, a painful thumb tendon condition. 62 adults with the condition received one of the two injections. Researc…
Phase 4 • Sponsor: OrthoCarolina Research Institute, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Can too much screen time weaken teen hands?
Knowledge-focused CompletedThis study looks at whether a painful hand condition called De Quervain's tenosynovitis, linked to heavy smartphone use, affects hand grip strength and quality of life in teenagers. Researchers will compare two groups of smartphone-addicted adolescents: those with the condition a…
Sponsor: Mariam Mohamed Sherif • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC