Steroid or painkiller shot: which works better for thumb tendonitis?
NCT ID NCT02604537
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a steroid injection (betamethasone) or a nonsteroidal anti-inflammatory injection (ketorolac) better relieves pain from DeQuervain's tenosynovitis, a painful thumb tendon condition. 62 adults with the condition received one of the two injections. Researchers measured pain during a specific thumb movement and at rest to see which treatment worked better.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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62 people
The number who actually took part.
- Started
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Oct 2015
- Finished
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Oct 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of DeQuervain tendinopathy * Understands the local language and is willing and able to follow the requirements of the protocol * Understands the informed consent and signs the institutional review board/independent ethics committee (IRB/IEC) approved informed consent form Exclusion Criteria: * Patients who have an allergy to lidocaine, celestone, or ketorolac, nonsteroidal anti-inflammatory drugs (NSAIDs), or acetylsalicylic acid (ASA) * Patients who have an adverse reaction to lidocaine, celestone, or ketorolac (such as severe elevation of blood sugars in diabetics that caused medical complication) * Patients who have received a prior steroid injection within the past three months * Patients who have had a prior ipsilateral surgery for DeQuervain Tenosynovitis * Patients that have a skin lesion at the location of injection (such as trauma, eczema, rash) * Patients who have a current infection at the location of injection * Patients who have had iontophoresis within three months * Patients who are breast feeding, pregnant, or who plan to become pregnant in the next six months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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OrthoCarolina
Charlotte, North Carolina, 28207, United States
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