Cystic fibrosis-related diabetes
MONDO:7770003A form of diabetes mellitus unique to individuals with cystic fibrosis (CF), arising primarily from progressive fibrotic destruction of the pancreas leading to insulin deficiency, with additional contributions from insulin resistance. CFRD affects approximately 20% of adolescents and 40-50% of adults with CF. It shares features with both type 1 and type 2 diabetes but is a distinct clinical entity with its own diagnostic criteria and management guidelines.
Also known as: CF-related diabetes, CFRD
55 clinical trials for this condition and its sub-types, 22 tagged with Cystic fibrosis-related diabetes itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Part of
-
Could ozempic help cystic fibrosis diabetes? tiny study hints at yes
Disease control CompletedThis pilot study tested the drug semaglutide (a GLP-1 receptor agonist, like Ozempic) in 8 overweight or obese adults with cystic fibrosis-related diabetes who were already using insulin. The goal was to see if adding semaglutide could safely help with weight loss and improve blo…
Phase 2/3 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
-
Which insulin dosing method works best for cystic fibrosis diabetes?
Disease control CompletedThis study tested two common methods of dosing mealtime insulin in people with cystic fibrosis-related diabetes: counting carbohydrates versus using a fixed dose. Researchers used continuous glucose monitors to track blood sugar levels and see which method kept glucose in a healt…
Phase 4 • Sponsor: Jagdeesh Ullal • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
-
Glucose sensor may flag diabetes risk in cystic fibrosis
Diagnosis CompletedPeople with cystic fibrosis often develop prediabetes and then diabetes, but doctors lack a good way to predict who will progress. This pilot study at Indiana University tests whether a continuous glucose monitor worn for up to 10 days, combined with a mathematical model called t…
Sponsor: Indiana University • Aim: Diagnosis
Last updated Sep 19, 2026 00:00 UTC
-
Blood test tracks diabetes risk in cystic fibrosis patients
Knowledge-focused CompletedThis study looked at whether a blood test can measure beta cell death in people with cystic fibrosis, which may help predict diabetes. About 40 participants with cystic fibrosis and healthy controls gave blood samples to check for a specific DNA marker. The goal was to understand…
Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
-
Sleep and blood sugar link explored in cystic fibrosis diabetes study
Knowledge-focused CompletedThis completed study looked at how blood sugar levels affect sleep in 30 adults with cystic fibrosis-related diabetes. Participants wore devices at home to track glucose and sleep for 10 days. The goal was to see if this kind of remote monitoring is practical and to gather early …
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
-
Cystic fibrosis diabetes mystery: why does it sometimes go away?
Knowledge-focused CompletedThis study followed 230 people with cystic fibrosis to understand why some develop diabetes and why it sometimes reverses. Researchers tracked genetics, lung health, infections, diet, and physical activity over a year. The goal is to improve how diabetes is screened and treated i…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:08 UTC