Cystic fibrosis diabetes mystery: why does it sometimes go away?
NCT ID NCT01072708
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study followed 230 people with cystic fibrosis to understand why some develop diabetes and why it sometimes reverses. Researchers tracked genetics, lung health, infections, diet, and physical activity over a year. The goal is to improve how diabetes is screened and treated in cystic fibrosis patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better ways to predict and manage diabetes in cystic fibrosis patients, potentially improving their quality of life.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly test any new therapy, so any benefits are indirect and may take years to apply.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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230 people
The number who actually took part.
- Start date
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Apr 2009
- Finished
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Oct 2014
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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10 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Cystic fibrosis patients with at least one visit in Cystic fibrosis Center in Rhône-Alpes (France) during the second half-year 2008 * Patients with disorders or not of the glucose metabolism * Patient with pancreatic insufficiency Exclusion Criteria: * Patient with hypoglycemia treatment : insulin or oral antidiabetic * Patient with an age \< 10 years * Patient with lung transplant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Service de Médecine Interne - Centre Hospitalier Lyon Sud
Pierre-Bénite, 69495, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a simple questionnaire reveal why some cystic fibrosis patients skip physiotherapy?
- Cystic fibrosis diabetes: do gut hormones and genes hold the key?
- Can a special lung scan catch cystic fibrosis damage earlier than standard tests?
- Can a pill replace the liquid? testing a new form of cystic fibrosis drug
- Triple therapy under the microscope: does it transform cystic fibrosis care?