Coronavinae infectious disease

This early-stage trial tests a new booster vaccine called Boost-2867 in 140 healthy adults who have already been vaccinated against COVID-19. The vaccine is given either as a shot with or without adjuvants (ingredients that boost immune response) or as a nasal spray without adjuv…

This study tests two updated mRNA COVID-19 vaccines (mRNA-1283 and mRNA-1273 variant formulation) in 30,000 healthy adults aged 50 to 64 who are not at high risk for severe COVID-19. The goal is to see if these vaccines prevent symptomatic COVID-19 compared to a placebo. Research…

This Phase 3 trial tests whether hydroxychloroquine, given alone or with azithromycin, can improve outcomes for adults hospitalized with moderate to severe COVID-19 lung disease. Participants receive hydroxychloroquine for 10 days, and some also get azithromycin for 5 days. Resea…

This study was designed to test whether the drug itolizumab could help hospitalized COVID-19 patients recover faster. The trial was planned for 18 years and older with confirmed COVID-19 pneumonia and low oxygen levels. However, the study was withdrawn before enrolling any partic…

This study aimed to see if the drug sarilumab could help hospitalized COVID-19 patients with severe breathing distress. It planned to compare one or two doses of sarilumab against a placebo. However, the study was withdrawn before enrolling any participants, so no results are ava…

Researchers are studying whether people can accurately use a rapid COVID-19 antibody test at home. Participants in New York City who have recovered from or suspect they had COVID-19 take the finger-prick test themselves and photograph the result for a doctor to check. The study a…

This study aimed to see if the BCG vaccine, originally for tuberculosis, could reduce the severity of COVID-19 in healthcare workers in Medellín, Colombia. It planned to give a single dose of BCG or a placebo to 0 participants (doctors, nurses, and nursing assistants) who were di…

This study follows 583 adults who recovered from COVID-19 or were close contacts. Researchers will track their health, mental well-being, and immune responses over 3 years to understand long-term effects and whether prior infection prevents reinfection. Participants undergo regul…

The KIDCOV study investigates whether mild or asymptomatic COVID-19 that does not require hospitalization increases the risk of kidney injury. Researchers enroll 2,000 adults who tested positive or negative for COVID-19, balanced by race and ethnicity across California, Michigan,…

This nationwide study follows thousands of pregnant women from early pregnancy through the first year of their baby's life to understand how COVID-19 infection affects both mother and child. Researchers will track infections, including those without symptoms, and compare pregnanc…

This study follows 500 ICU patients to compare long-term mental and physical health between those with and without COVID-19. Researchers use surveys and tests to measure quality of life, thinking skills, and emotional well-being. The goal is to identify specific problems caused b…

This study looks at how the immune system of patients in the intensive care unit (ICU) responds to severe infections caused by viruses or bacteria. Researchers will take extra blood samples from 38 adults to analyze immature granulocytes, a type of immune cell. The goal is to see…

This study planned to test telemonitoring for older adults (75+) in nursing homes with confirmed or probable COVID-19. The goal was to see if remote monitoring could improve healthcare management and reduce deaths within 30 days. However, the study was withdrawn before enrolling …

This study collects blood samples and medical information from 201 adults diagnosed with COVID-19. The goal is to create a resource that researchers can use to study the virus and improve understanding of the disease. Participants provide samples and allow their health data to be…

This study is creating a biobank of blood samples and health data from 100 people who have recovered from COVID-19. Researchers will use this information to better understand recovery and long-term effects. No new treatments are being tested; the goal is to provide resources for …

This study tracks over 4,200 people in South Korea who received a SPIKEVAX COVID-19 vaccine to see if any side effects occur over time. Participants are aged 12 or older depending on the vaccine version. The goal is to gather real-world safety data, not to test if the vaccine wor…

This study tests whether temperature sensors placed inside a Venturi mask can monitor breathing patterns in 82 patients hospitalized with pneumonia and respiratory failure. The goal is to see if these patterns can detect early signs of deterioration before patients need a breathi…