Congenital syphilis

MONDO:0005714

A life-threatening bacterial infection of the newborn caused by Treponema pallidum. It is transmitted to the infant from a mother with syphilis through the placenta during pregnancy. Signs and symptoms include irritability, fever, failure to thrive, saddle nose, cutaneous rash, and pneumonia.

Also known as: MTCT of syphilis, congenital syphilis, mother-to-child transmission of syphilis

16 clinical trials for this condition and its sub-types, 7 tagged with Congenital syphilis itself.

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Where it sits in the disease tree

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Part of

↑ Syphilis (56) ↑ Infectious embryofetopathy (25)

Sub-types of Congenital syphilis

Early congenital syphilis 0 trials
Late congenital syphilis 0 trials

Including sub-types (16) Tagged with Congenital syphilis (7)

Trials to join now! 6 Not yet recruiting 4 Not yet finished but already full! 1 Completed 5

New tetracycline drugs take on superbugs in Real-World trial

Disease control By invitation only

This real-world study is testing two neotetracycline drugs, eravacycline and tigecycline, in 300 adults with drug-resistant Gram-negative bacterial infections. Researchers will track how well the drugs clear the infection and monitor for side effects. The goal is to see if these …

Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control

Last updated Jun 27, 2026 08:09 UTC

Congenital syphilis

Where it sits in the disease tree

New tetracycline drugs take on superbugs in Real-World trial