Complex regional pain syndrome type 2

This study is testing a new way to use an already-approved spinal cord stimulator to treat chronic, hard-to-manage back and leg pain. The device sends mild electrical pulses to the spine, and the new setting (called TVP-SCS) varies the timing of those pulses. Researchers will enr…

This study will follow 80 people with chronic pain (like back, hip, or nerve pain) who are getting a procedure called cryoneurolysis, which uses cold to temporarily block pain signals. Researchers want to see if it leads to meaningful pain relief and better daily function over 12…

This European study will test a new type of spinal cord stimulation device in 200 people with persistent back and leg pain after failed back surgery. The device uses a special stimulation pattern to try to reduce pain. Researchers will track pain levels and device settings to see…

This study is testing whether a single injection of botulinum toxin (similar to Botox) around major nerves can safely reduce pain in people with Complex Regional Pain Syndrome (CRPS), a chronic condition causing severe pain and disability. Twenty adults with CRPS in one arm or le…

This study tests whether adding a non-invasive brain stimulation technique called tDCS to a structured exercise program can reduce pain and disability in adults with chronic spinal pain that hasn't improved with usual care. Forty-two participants will be randomly assigned to rece…

This study tests whether a spinal cord stimulator can reduce long-term leg pain in people who still have pain after lumbar spine surgery. Fifty adults aged 18-70 who have not improved with other treatments will receive either active stimulation or sham (no stimulation) for 3 mont…

This study tests whether using a closed-loop spinal cord stimulator early in complex regional pain syndrome (CRPS) works better than waiting until the chronic phase. The device automatically adjusts its settings based on the body's signals. Researchers will enroll 32 adults with …

This study tests whether a personalized rehabilitation program helps people with persistent spinal pain syndrome type II (failed back surgery syndrome) return to work after receiving a spinal cord stimulator. 112 participants will be randomly assigned to either the personalized p…

This pilot study looks at how lowering doses of pain medications like opioids and gabapentinoids changes the way the spinal cord responds to closed-loop spinal cord stimulation. Twenty adults with failed back surgery syndrome will be followed during a 21-day trial and up to 6 mon…

This study looks at how different pain medications change the way the spinal cord responds to a special type of spinal cord stimulator. The device automatically adjusts its stimulation based on nerve signals. Researchers will follow 50 people with chronic back pain who are either…