Clear cell renal carcinoma
MONDO:0005005A malignant epithelial neoplasm of the kidney characterized by the presence of lipid-containing clear cells within a vascular network. The tumor may metastasize to unusual sites and late metastasis is common.
Also known as: Grawitz tumor, Grawitz tumour, RCC, clear cell adenocarcinoma, clear cell adenocarcinoma of kidney, clear cell adenocarcinoma of the kidney, clear cell adenocarcinoma, kidney, clear cell carcinoma of kidney, clear cell carcinoma of the kidney
2904 clinical trials for this condition and its sub-types, 140 tagged with Clear cell renal carcinoma itself.
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Sub-types of Clear cell renal carcinoma
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Can a year of sunitinib delay kidney Cancer's return after lung surgery?
Disease control Stopped earlyThis phase 2 trial investigates whether taking the drug sunitinib for one year after surgical removal of lung metastases can improve relapse-free survival in patients with clear cell kidney cancer. Participants are randomly assigned to receive either sunitinib or a placebo follow…
Phase 2 • Sponsor: Association of Urologic Oncology (AUO) • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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New drug combo tested for advanced kidney cancer shows promise but study halted early
Disease control Stopped earlyThis study tested a combination of two drugs, sitravatinib and nivolumab, in people with advanced kidney cancer that had spread and worsened after prior treatment. The goal was to see if the combination could shrink tumors or slow the disease. The study was stopped early after en…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:04 UTC
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Gene therapy trial for advanced kidney cancer halted early
Disease control Stopped earlyThis study tested a one-time gene therapy called Temferon in 10 people with advanced kidney cancer that had worsened after standard treatments. The goal was to see if it was safe and could activate the immune system against tumors. The trial was terminated early, so results are l…
Phase 1/2 • Sponsor: Genenta Science • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Experimental cancer drug TAK-500 tested in 61 patients – study halted early
Disease control Stopped earlyThis early-phase trial tested an experimental drug called TAK-500, alone or with the immunotherapy pembrolizumab, in 61 adults with advanced solid tumors like pancreatic, liver, and lung cancer. The main goals were to check safety and see if the drug could shrink tumors. The stud…
Phase 1/2 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Kidney cancer drug combo trial halted early – what we know
Disease control Stopped earlyThis early-stage trial tested a combination of two immunotherapy drugs, aldesleukin (IL-2) and pembrolizumab, in 6 people with advanced kidney cancer that had spread. The goal was to find the safest dose and see if the combination could shrink tumors. The study was terminated ear…
Phase 1 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Kidney cancer drug combo tested before surgery – study halted early
Disease control Stopped earlyThis study looked at whether giving the immunotherapy drug pembrolizumab (with or without axitinib) before surgery could help control advanced kidney cancer. Only 6 people took part before the study was stopped early. The goal was to see if the treatment boosted immune cells in t…
Phase 2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Kidney cancer combo trial halted early – what we know
Disease control Stopped earlyThis study tested a new drug (NKT2152) combined with two other medicines (palbociclib and sasanlimab) in people with advanced clear cell kidney cancer that had worsened after prior treatments. The goal was to see if the combination was safe and could shrink tumors. The trial was …
Phase 2 • Sponsor: NiKang Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC