Chronic ulcer of skin
MONDO:0004605Also known as: callous ulcer (morphologic abnormality), indolent ulcer (morphologic abnormality)
270 clinical trials for this condition and its sub-types, 48 tagged with Chronic ulcer of skin itself.
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Sub-types of Chronic ulcer of skin
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Decubitus ulcer 138 trials
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Ulcer of lower limbs 124 trials
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Amniotic membrane wrap studied for stubborn leg sores in seniors
Disease control Stopped earlyThis study tested a special wrap made from donated placenta tissue (human amniotic membrane) to help heal difficult leg ulcers caused by poor blood flow in people aged 65 and older. The goal was to see if the wrap could close the wound completely within 12 weeks. The trial was st…
Sponsor: BioLab Holdings • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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New synthetic skin patch tested for Hard-to-Heal wounds
Disease control Stopped earlyThis study tested a man-made skin substitute called Restrata for treating diabetic foot ulcers and venous leg ulcers. For diabetic foot ulcers, Restrata was compared to standard wound care. For venous leg ulcers, it was compared to a living cell-based skin substitute (Apligraf). …
Sponsor: Acera Surgical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Smart wheelchair cushion aims to stop pressure sores
Prevention Stopped earlyThis study tested a special seat cushion (GASPARD®) that measures pressure and sends alerts to a smartphone to help prevent pressure sores in people with spinal cord injuries. The trial included 134 participants who used manual wheelchairs. Unfortunately, the study was terminated…
Sponsor: Nantes University Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:10 UTC
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New wound pump shows promise for stubborn leg ulcers
Symptom relief Stopped earlyThis study tested whether a single-use negative pressure wound therapy system (PICO) helps heal hard-to-treat venous leg ulcers better than standard care. About 142 adults with leg ulcers that had lasted at least 6 weeks took part. The main goal was to see if more ulcers healed c…
Sponsor: Smith & Nephew, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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New wound vacuum dressing shows promise in small study
Symptom relief Stopped earlyThis study tested a new type of wound vacuum dressing on 7 people with chronic or acute wounds. The goal was to see if the dressing helps wounds heal or get better. The study was stopped early, so results are limited.
Sponsor: Smith & Nephew, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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New tool aims to spot wound healing hurdles early
Knowledge-focused Stopped earlyThis study is for people with wounds that have developed hypergranulation (overgrown tissue that slows healing). Researchers will take photos and use a new assessment tool to grade the severity. About 100 adults and children in the UK will take part. The goal is to create a stand…
Sponsor: Ennogen Healthcare Limited • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC