Chronic ulcer of skin

This trial tests whether adding vacuum compression therapy — a device that applies cycles of pressure and suction to the leg — can improve healing of chronic lower limb ulcers. Adults with ulcers that have not healed despite standard care will receive either standard wound care a…

This phase 3 trial investigates whether the antibiotic linezolid can cure yaws, a bacterial skin infection that causes ulcers, as effectively as the standard treatment azithromycin. The study involves 384 children aged 5 to 18 with confirmed yaws. Participants receive either line…

This study tests whether using telemedicine (remote doctor visits) helps heal chronic wounds better than usual in-person care. Adults with long-lasting wounds in the Languedoc-Roussillon region of France are randomly assigned to telemedicine or standard treatment. The main goal i…

This study tested a wound patch called Oasis ECM on 41 people with non-healing sores. The patch is made from natural material to help wounds heal. Researchers measured how much the wounds closed and how patients felt about their quality of life.

This study tested whether a special dressing made from a patient's own platelets (platelet-rich plasma) helps chronic wounds heal better than a standard saline dressing. One hundred adults with long-lasting skin ulcers, including diabetic foot ulcers, took part. The goal was to s…

This phase 2b trial tested a one-time application of a cell therapy made from donor skin cells (Allo-APZ2-CVU) in 159 people with chronic venous leg ulcers that hadn't healed despite standard care. The goal was to see if it could shrink or close these wounds better than a placebo…

This study tested whether taking fish oil supplements (EPA and DHA) could help heal chronic venous leg ulcers in adults aged 55 and older. The idea was that fish oil might reduce inflammation at the wound site, allowing the ulcer to heal. Researchers measured changes in blood mar…

This study collected fluid from the wounds of 13 people with hard-to-heal leg ulcers. Researchers analyzed the fluid to see how it affects skin cells and bacteria. The goal was to learn more about why some wounds don't heal, not to test a new treatment.

This study tested whether a smartphone app called MyDerm can help patients and doctors monitor chronic leg wounds from home. 25 adults with a single leg wound that had lasted more than 6 weeks took part. Patients used the app to take photos of their wound and answer questions abo…

This study tested a computer program called ACE that helps nurses decide which products to use for treating chronic wounds. Researchers compared outcomes when nurses used ACE versus their usual approach in 73 patients across 18 clinics. The goal was to see if the tool improves he…