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Can Platelet-Rich plasma heal stubborn wounds faster than saline?

NCT ID NCT07420868

Disease control Sponsor: Multan Medical And Dental College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special dressing made from a patient's own platelets (platelet-rich plasma) helps chronic wounds heal better than a standard saline dressing. One hundred adults with long-lasting skin ulcers, including diabetic foot ulcers, took part. The goal was to see if the platelet dressing could shrink the wound more over six weeks and reduce pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Mar 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or above * Either gender * Chronic non healing cutaneous ulcer of at least 6 weeks duration * Ulcer etiology eligible for conservative dressing-based management, including * Diabetic foot, Venous leg and Pressure ulcer * Other chronic ulcers considered suitable by the treating dermatologist * Measurable index ulcer surface area suitable for standardized photography and planimetric assessment * Clinically acceptable wound bed after initial wound bed preparation * No requirement for urgent surgical reconstruction at enrolment * Ability to attend twice weekly dressing visits for 6 weeks * Provision of written informed consent Exclusion Criteria: * Suspected or proven malignant ulceration * Vasculitic or inflammatory ulcers requiring systemic immunosuppression * Pyoderma gangrenosum * Critical limb ischemia or severe perfusion compromise on clinical assessment, with vascular screening where feasible * Requirement for urgent revascularization * Active osteomyelitis requiring bony debridement * Exposed bone with high suspicion of osteomyelitis * Rapidly spreading soft tissue infection * Systemic sepsis * Hematological abnormalities making venesection or platelet rich plasma preparation unsafe, including * Clinically relevant platelet dysfunction * Known bleeding diathesis * Therapeutic anticoagulation where temporary interruption is not clinically appropriate * Pregnancy or lactation * Participation in another interventional wound trial * Inability to comply with follow up

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Conditions

The condition(s) this trial relates to.

chronic ulcer of skin decubitus ulcer Diabetic Foot ulcer of lower limbs

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic skin ulcer Diabetic foot ulcer

Contacts and locations

Locations

  • Multan Medical and Dental College

    Multan, Punjab Province, 60000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.