Chronic pancreatitis

This study tested two anti-inflammatory drugs (etanercept and alpha-1 antitrypsin) in 43 adults with severe chronic pancreatitis who had their pancreas removed and their insulin-making cells (islets) transplanted into the liver. The goal was to see if these drugs could protect th…

This study compared robotic-assisted pancreatic surgery to the standard open approach for people with pancreatic and related tumors. Researchers wanted to see if robotic surgery could help patients recover faster after the operation. A total of 268 patients took part across multi…

This study follows people with a significantly elevated risk of pancreatic cancer—due to inherited gene mutations or strong family history—who choose to undergo early detection testing. Participants receive endoscopic ultrasound (EUS) and MRI scans on an alternating schedule ever…

This study looked at new markers in blood and urine to detect and predict the severity of drug-associated acute pancreatitis in adults. Researchers compared these markers in 175 patients with drug-induced pancreatitis, other pancreatic diseases, and healthy volunteers. The goal i…

This study tested whether a procedure called ERCP with sphincterotomy can lower the risk of repeat pancreatitis attacks in people with pancreas divisum, a condition where the pancreas ducts don't join normally. 181 adults who had at least two pancreatitis episodes were randomly a…

This study compared two devices used during a procedure called ERCP to remove stones from the pancreatic duct in people with chronic pancreatitis. One group used a basket first, the other a balloon first. The goal was to see which tool cleared more stones. A total of 104 adults w…

This study tested whether a web-based self-management program is feasible and acceptable for people with chronic pancreatitis who have ongoing abdominal pain. Thirty-one participants were given access to a tailored website with pain management modules over 12 weeks. The goal was …

This study tested a web-based program to help children aged 10-19 with chronic or recurring pancreatitis manage their abdominal pain. The program teaches cognitive behavioral skills to reduce pain and improve quality of life. 90 participants were enrolled, and the study measured …

This study tested a small, needle-free device that sends mild electrical pulses to specific points on the skin to relieve abdominal pain in people with chronic pancreatitis. 42 adults with long-term pancreas pain used the device at home for several weeks. The goal was to see if t…

This small pilot study tested a safe, non-invasive device that uses mild electrical pulses on the skin to help reduce belly pain in people with chronic pancreatitis. The goal was to see if patients would use the device at home and if it could be a drug-free option for pain. The s…

This study looked at 220 adults with chronic pancreatitis and large pancreatic stones to find the best time to perform an endoscopic procedure after shock wave lithotripsy (ESWL). The goal was to improve stone clearance and reduce complications. Results help doctors plan treatmen…

This study tested whether a procedure called pancreatic endotherapy can reduce pain in people with chronic pancreatitis whose main pancreatic duct is blocked by stones or narrowings. Fourteen adults with severe daily pain were randomly assigned to get either an ultrasound alone o…

This study compares two procedures for breaking up large stones in the pancreatic duct of people with chronic pancreatitis. One method uses shock waves from outside the body, while the other uses a tiny scope and laser during an ERCP. The goal is to see which technique clears sto…

This study creates a registry of adults with pancreatic exocrine insufficiency (PEI), a condition where the pancreas does not produce enough enzymes to digest food properly. Researchers at eight specialist centers across Europe will track how doctors prescribe pancreatic enzyme r…

This completed study created a registry of 400 adults with exocrine pancreatic insufficiency (EPI) caused by chronic pancreatitis. Researchers collected real-world data on disease history, treatment patterns, and quality of life through patient reports and clinic visits. The goal…

This study looked at whether measuring pancreatic polypeptide levels after a meal can help doctors tell the difference between type 1 diabetes and type 3c diabetes (caused by pancreas damage). Thirty-six adults with either type 1 or type 3c diabetes gave blood and stool samples. …

This study looked at whether enzyme therapy helps people with chronic pancreatitis absorb protein better. Eleven participants took part to measure how their bodies used dietary nitrogen. The goal was to understand if current enzyme treatments are effective for protein digestion.

This study tested a computer model (XGBoost) to predict whether suspicious spots on CT scans in people with chronic pancreatitis are cancerous. Researchers analyzed data from 113 patients to see how accurate the model was. The goal is to help doctors make better decisions without…

This study tested the EchoTip AcuCore, a needle used during endoscopic ultrasound to collect tissue samples from the pancreas, liver, and other organs. 183 adults with conditions like cancer or chronic pancreatitis took part. The main goal was to see if the needle could get a goo…