Cholelithiasis
MONDO:0012672The presence of crystallized deposits forming in the gallbladder or biliary tree, primarily composed of cholesterol, bilirubin, and bile.
Also known as: gallstones
108 clinical trials for this condition and its sub-types, 74 tagged with Cholelithiasis itself.
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Sub-types of Cholelithiasis
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Choledocholithiasis 40 trials
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Cholecystolithiasis 14 trials
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Gallbladder disease 1 1 trial
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Primary intrahepatic lithiasis 0 trials
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Voice-Controlled robot aids surgeons in first human gallbladder operations
Disease control OngoingThis early study tests whether a voice-controlled AI-assisted robotic system can safely help surgeons perform gallbladder removal. Ten adults with symptomatic gallstones or gallbladder polyps will undergo the procedure. The main goal is to see if the surgery can be completed with…
Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New study tests single surgery to clear bile duct stones faster
Disease control OngoingThis study looks at 100 people with gallstones that have moved into the bile duct. One group gets the usual two-step treatment: first a scope to remove the bile duct stone, then surgery to remove the gallbladder. The other group gets a single surgery where the gallbladder is remo…
Sponsor: Riga East Clinical University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Pain block showdown: one side or two for gallbladder surgery?
Symptom relief By invitation onlyThis study looks at two ways to give a pain-relieving injection (TAP block) to people having their gallbladder removed by keyhole surgery. One group gets the injection only on the right side, the other gets it on both sides. Researchers will track how long it takes before patient…
Sponsor: King Edward Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Pre-Surgery lessons boost recovery after gallbladder removal
Symptom relief OngoingThis study looks at whether teaching patients about gallstones and gallbladder removal surgery before the operation can improve their quality of life afterward. About 200 adults having gallbladder surgery will either get standard hospital care or extra educational sessions. Resea…
Sponsor: Hawler Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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New wash may ease pain and nausea after gallbladder surgery
Symptom relief OngoingThis study tests whether adding the anti-nausea drug ondansetron to a standard saline wash during gallbladder surgery can better control pain and nausea afterward. Forty adults having their gallbladder removed will be randomly assigned to receive either a plain saline wash or one…
Phase 4 • Sponsor: Instituto Mexicano del Seguro Social • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Which ventilation mode breathes better during laparoscopic surgery?
Knowledge-focused OngoingThis trial compares two ways of delivering mechanical ventilation—volume-controlled and pressure-controlled—in adults undergoing laparoscopic gallbladder removal under general anesthesia. The goal is to see which mode better maintains lung flexibility and removes carbon dioxide d…
Sponsor: Mehreen Mirza • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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New registry aims to improve bile duct stone removal
Knowledge-focused OngoingThis study is a registry that collects information from patients who have a procedure called percutaneous cholangiopancreatoscopy (PCPS). During PCPS, doctors use a tiny camera to see inside the bile ducts and remove stones or take tissue samples. The goal is to learn how well th…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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120,000-Person study hopes to crack the code of chronic illness
Knowledge-focused PausedThis observational study plans to enroll 120,000 people with various chronic diseases like pancreatitis, diabetes, and arthritis. Researchers will collect blood samples and health data to study how genetics and lifestyle affect disease progression. The goal is to find common dise…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC