Central nervous system infectious disorder
MONDO:0024619An infectious process that affects the brain and/or spinal cord. Representative examples include encephalitis, poliomyelitis, arachnoiditis, and meningitis.
Also known as: central nervous system infectious disease, central nervous system infectious disorder, infectious disease of central nervous system, central nervous system infection, infections, central nervous system
163 clinical trials for this condition and its sub-types, 10 tagged with Central nervous system infectious disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Central nervous system infectious disorder
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Viral infection of central nervous system 3 trials · 58 incl. sub-types
7 sub-types
- Poliomyelitis 28 trials · 39 incl. sub-types Sub-types →
- Viral encephalitis 3 trials · 17 incl. sub-types Sub-types →
- Venezuelan equine encephalitis 1 trial
- Lymphocytic choriomeningitis 1 trial
- Central nervous system AIDS arteritis 0 trials
- Geniculate herpes zoster 0 trials
- Meningitis caused by poliovirus 0 trials
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Infectious encephalitis 3 trials · 50 incl. sub-types
10 sub-types
- Progressive multifocal leukoencephalopathy 19 trials
- Viral encephalitis 3 trials · 17 incl. sub-types Sub-types →
- Postinfectious encephalitis 0 trials · 13 incl. sub-types Sub-types →
- Hendra virus infection 0 trials
- Kluver-Bucy syndrome 0 trials
- Mycoplasma encephalitis 0 trials
- Acute necrotizing encephalopathy of childhood 0 trials
- Granulomatous amebic encephalitis 0 trials
- Primary amebic meningoencephalitis 0 trials
- Syphilitic encephalitis 0 trials
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Infectious meningitis 3 trials · 49 incl. sub-types
5 sub-types
- Bacterial meningitis 12 trials · 37 incl. sub-types Sub-types →
- Fungal meningitis 3 trials · 10 incl. sub-types Sub-types →
- Viral meningitis 5 trials · 6 incl. sub-types Sub-types →
- Arachnoiditis 0 trials Sub-types →
- Meningitis caused by poliovirus 0 trials
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Prion disease 5 trials · 11 incl. sub-types
10 sub-types
- Creutzfeldt Jacob disease 4 trials · 7 incl. sub-types Sub-types →
- Fatal familial insomnia 4 trials
- Gerstmann-Straussler-Scheinker syndrome 1 trial
- Huntington disease-like 1 0 trials
- PrP systemic amyloidosis 0 trials
- Familial Alzheimer-like prion disease 0 trials
- Kuru 0 trials
- Scrapie 0 trials
- Spongiform encephalopathy with neuropsychiatric features 0 trials
- Sporadic fatal insomnia 0 trials
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Central nervous system tuberculosis 1 trial · 7 incl. sub-types
1 sub-type
- Meningeal tuberculosis 7 trials
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Epidural abscess 5 trials
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Intracranial abscess 3 trials
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Cerebral malaria 2 trials
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Congenital toxoplasmosis 2 trials
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Human prion disease 1 trial
4 sub-types
- Acquired human prion disease 0 trials
- Kuru 0 trials
- Sporadic fatal insomnia 0 trials
- Variably protease-sensitive prionopathy 0 trials
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Subdural empyema 1 trial
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Neuroschistosomiasis 0 trials
Most studied deeper sub-types
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Engineered immune cells take on viruses in cancer patients
Disease control Stopped earlyThis early-stage trial is testing whether genetically modified T-cells can safely control viral infections in cancer patients with weakened immune systems. The T-cells are designed to target specific viruses like CMV, BK virus, or COVID-19. The study involves 30 participants and …
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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Polio Survivors' hope dashed: trial of immune treatment halted early
Disease control Stopped earlyThis study tested a blood product called immune globulin (Flebogamma) in 191 people with post-polio syndrome, a condition causing new muscle weakness years after polio. The goal was to see if it could improve walking distance and reduce pain. The trial was terminated early, so we…
Phase 2/3 • Sponsor: Instituto Grifols, S.A. • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Could emotional awareness therapy soothe mysterious body aches?
Symptom relief Stopped earlyThis pilot study tests whether a short-term group therapy called Emotional Awareness and Expression Therapy (EAET) can help people with persistent physical symptoms like pain or fatigue that have no clear medical cause. The therapy focuses on helping participants identify and exp…
Sponsor: Daniel Maroti • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Nose drops with friendly bacteria could pave way for meningitis vaccine
Knowledge-focused Stopped earlyThis study gave healthy adults nose drops containing a harmless bacteria (N. lactamica) to see how the body's immune system responds. The goal is to learn if the immune response is the same whether the bacteria is cleared after 4 days or 14 days. This information will help design…
Sponsor: University Hospital Southampton NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC