Catecholaminergic polymorphic ventricular tachycardia 1
MONDO:0011484Polymorphic ventricular tachycardia induced by adrenergic stress. It is inherited in an autosomal dominant pattern and is caused by mutations in the ryanodine receptor 2 (RYR2) gene.
Also known as: ARVC2, ARVD2, RYR2 familial isolated arrhythmogenic right ventricular dysplasia, arrhythmogenic right ventricular cardiomyopathy 2, arrhythmogenic right ventricular dysplasia 2, arrhythmogenic right ventricular dysplasia type 2, arrhythmogenic right ventricular dysplasia, familial, type 2, catecholaminergic polymorphic ventricular tachycardia 1
43 clinical trials for this condition and its sub-types, 2 tagged with Catecholaminergic polymorphic ventricular tachycardia 1 itself.
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New heart lead under watch: 5-Year safety check begins
Disease control By invitation onlyThis study follows 2000 people who have or will get the OmniaSecure defibrillation lead, a wire that helps control dangerous heart rhythms. Researchers will track how often the lead causes problems over 5 years. The goal is to make sure the lead is safe and works as expected in e…
Sponsor: Medtronic • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Could a short course of steroids calm a dangerous heart rhythm?
Disease control By invitation onlyThis trial tests whether an 8-week course of the immunosuppressive drug prednisone can reduce episodes of ventricular tachycardia (a potentially fatal fast heart rhythm) and improve heart function in people with non-ischemic cardiomyopathy and confirmed heart inflammation. Partic…
Phase 4 • Sponsor: Roderick Tung • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
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New antibiotic pouch aims to stop infections in heart device patients
Disease control OngoingThis study is tracking 100 adults who receive an EluPro antibiotic-eluting envelope during implantation of a heart device (like a pacemaker). The envelope slowly releases antibiotics to prevent infection. Researchers are monitoring complication rates in real-world use to see how …
Sponsor: Elutia Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Super MRI could spot hidden heart damage
Diagnosis OngoingThis study tests whether a new, more powerful 7 Tesla MRI can better detect scarring and swelling in the heart muscle of people with cardiomyopathy. Researchers will scan 13 adults aged 20-70 to see if the higher-resolution images improve diagnosis. The goal is to see if this adv…
Sponsor: University of Pennsylvania • Aim: Diagnosis
Last updated Jun 27, 2026 09:02 UTC
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Can a gene registry unlock the secrets of childhood heart failure?
Knowledge-focused OngoingThis study gathers health information from children under 18 who have cardiomyopathy linked to mutations in the MYBPC3 gene. Researchers aim to map the disease's natural course, identify risk factors, and measure how it affects quality of life. By reviewing past and future medica…
Sponsor: Tenaya Therapeutics • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Heart device DiamondTemp under Real-World watch: will it deliver?
Knowledge-focused OngoingThis registry follows 545 people with arrhythmia who received a heart ablation using the DiamondTemp system. Researchers will track how many stay free of their heart rhythm problem and how many have serious side effects over 12 months. The goal is to see how well the device works…
Sponsor: Medtronic Cardiac Ablation Solutions • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Ear zaps may tweak heart rhythms, tiny study hints
Knowledge-focused OngoingThis small pilot study is testing whether a gentle, non-invasive electrical stimulation on the ear (auricular vagus nerve stimulation) can change how the heart's electrical system works. Ten people who are already scheduled for a heart procedure will receive the stimulation while…
Sponsor: Northwell Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC