Brain infarction

This study tests whether the antibiotic minocycline can improve recovery in people who have had a major stroke and undergone a procedure to remove a blood clot from a large brain artery. Even when the clot is successfully removed, many patients still have significant disability. …

This study tests whether a noninvasive arm cuff therapy, called remote ischemic conditioning, can improve recovery in people who have had a major stroke and undergone a clot-removal procedure. The therapy involves briefly inflating and deflating a cuff on the upper arm to protect…

This study tests whether a specific set of anesthesia targets, called NeuroFirst, can reduce silent brain injury and thinking problems in older adults having heart surgery. About 900 patients aged 60 and older will be randomly assigned to either the NeuroFirst approach or standar…

This study tests whether a new CT-angiography method can accurately diagnose brain death compared to the standard four-vessel angiography. About 50 adults with severe brain injury will receive both tests. If the CT method works as well, it could offer a faster, less invasive way …

This study tests whether using EEG neurofeedback — a way to train brain activity — can improve arm movement in people who recently had a stroke. Forty adults with a stroke within the past three weeks will either get real or fake (sham) neurofeedback, plus standard rehab. The goal…

This study will follow 500 people who have had a stroke and also have atrial fibrillation (an irregular heartbeat). Some were taking blood thinners when they had their stroke, others were not. Researchers want to understand why blood thinners fail in some patients, by looking at …