Blindness (disorder)

This study tests whether intensive visual retraining at home can help people who have lost part of their vision due to damage to the brain's visual cortex, often from a stroke. Participants will use a computer program to practice detecting motion and orientation of visual stimuli…

This trial investigates whether bosentan, a drug that blocks endothelin and relaxes blood vessels, can help people who suddenly lose vision from giant cell arteritis (Horton's disease). Standard steroid treatment often fails to restore sight once blindness occurs. The study enrol…

This study tests a smart computer simulation (digital twin) of Saudi streets to train visually impaired people on safe navigation. Participants use 3D audio and a vibrating vest to learn to avoid obstacles. The goal is to see if this high-tech training reduces real-world collisio…

This early-phase trial tested the drug rituximab in 3 people with ocular cicatricial pemphigoid, a rare autoimmune disease that causes scarring in the eye and can lead to blindness. The goal was to see if the drug could stop further scarring when standard treatments had failed. T…

This study looked at whether giving exosomes through the nose could help improve vision in 32 children with cortical visual impairment (CVI), a vision problem caused by brain injury. The children received the treatment once a month for six months and were monitored for changes in…

This study tested an eye drop (POS) in 200 adults who had poor night vision after LASIK or similar eye surgery. The goal was to see if the drops could help them see better in dim light, reducing problems like glare and halos. Participants used the drops for 15 days and had their …

This small proof-of-concept study tested a non-invasive device that uses sound and light to help people with hemianopia (blindness in half of the visual field). Five adults with stable hemianopia underwent training sessions where they were exposed to matching sound and visual cue…

This study tested whether Nyxol eye drops can help people who have trouble seeing in dim light, often after eye surgeries like LASIK or cataract surgery. 144 adults received either the eye drops or a placebo for 8 days. The main goal was to see if Nyxol could improve vision in lo…

This study follows 61 people who previously used the REVISYON SDS 100 device for mild-to-moderate cataract. Researchers will check for side effects and measure vision changes over about 20 months. No new treatment is given; the goal is to see if the device stays safe and works we…

This study aims to find the genes that cause inherited hearing loss by analyzing DNA from 24,000 people in large Pakistani families. Researchers will compare affected and unaffected family members to identify new deafness genes. The goal is to improve genetic testing and counseli…

This trial tests whether a specially designed audio-described education program can improve menopause knowledge and reduce symptom severity in visually impaired women. About 46 women aged 40-60 who are members of a blind association will be randomly assigned to receive the progra…

This study aims to measure how common glaucoma is among people aged 50 and older in the Bangkoknoi district of Bangkok, Thailand. Researchers will examine about 1,470 volunteers using standard eye tests and advanced imaging to detect signs of glaucoma and gather normal eye measur…

This study tested whether a sing-along song can help visually impaired individuals aged 6 to 20 learn to brush their teeth better. Forty participants in Nepal were split into two groups: one received standard audio-tactile instruction, and the other heard a song with the same ins…

This study looked at whether hearing and vision loss are linked to delirium (sudden confusion) in older hospital patients. Over 1,500 participants answered screening questions and had their hearing and vision tested. In a smaller trial, researchers tested if posting communication…

This study looked at new ways to measure and train eye movements in 21 people with macular degeneration, a condition that causes central vision loss. The goal was to see if training could help them use their remaining side vision more effectively. The research focused on understa…