Bacterial urinary tract infection

When a kidney stone blocks urine flow and causes a severe infection, doctors must quickly relieve the blockage and control the infection. They can place a stent through the urinary tract, insert a drainage tube through the skin, or start antibiotics alone. This study observes 1,6…

This study tests whether a machine-learning system called iAST® can improve how doctors choose antibiotics for patients with pneumonia, urinary tract infections, or sepsis. The AI predicts which antibiotics are likely to work before standard lab results are available. Researchers…

This study is testing whether a new antibiotic combination, cefepime/enmetazobactam, works as well as the best current treatments for complicated urinary tract infections that have spread to the bloodstream. These infections are caused by bacteria resistant to many common antibio…

This study tests whether giving a daily antibiotic (pivmecillinam) to kidney transplant patients at high risk of bloodstream infections can reduce those infections. 150 participants will receive either the antibiotic or a placebo for 5 months after transplant. The goal is to see …

This early-stage trial is testing an experimental antibiotic called TUL108 in healthy volunteers to see if it is safe and how the body processes it. The drug is being developed for complicated urinary tract infections (cUTI), which can be difficult to treat with standard antibiot…

This early study tests whether a personalized mix of viruses (called phages) can safely treat urinary tract infections caused by drug-resistant bacteria. Six adults aged 18–65 will receive the phage cocktail through a catheter every 12 hours for 2–3 days. Researchers will monitor…

This trial investigates whether a rapid test for antibiotic resistance genes (integrons) can help doctors choose narrower-spectrum antibiotics for hospitalized adults with urinary tract infections (UTIs). Participants must have had a recent infection with a resistant bacterium. T…

This observational study looks at whether children aged 3 months to 16 years are more likely to complete their full course of antibiotics when prescribed at a primary care clinic versus a hospital emergency department. Researchers surveyed parents by phone after treatment ended t…

This study will see if using virtual care technologies in hospital units can reduce problems like patient falls, infections, and readmissions, while also improving patient satisfaction. About 10,000 adults admitted to six hospital units will take part, with three units using the …

This study examines the impact of removing urine dipstick tests for diagnosing urinary tract infections (UTIs) in hospitals in the North Denmark Region. Researchers will compare data from before and after the change, looking at UTI diagnoses, antibiotic use, lab tests, and patien…

This study looks at whether teaching patients about catheter care can improve their attitudes toward preventing infections and lower their anxiety after urologic surgery. About 70 male patients who go home with a urinary catheter will receive a training booklet based on daily liv…