Bacterial sexually transmitted disease

This study aimed to see if communities with low levels of trachoma could stop receiving yearly azithromycin treatments without the infection coming back. Researchers planned to compare groups that continued or stopped the medicine over three years. However, the trial was withdraw…

This study tests whether the antibiotic linezolid can effectively treat early syphilis in 24 adults. Participants have primary, secondary, or early latent syphilis, and some also have well-controlled HIV. The main goal is to see if linezolid reduces syphilis infection markers in …

This study tests whether giving antibiotics more often to entire communities can eliminate trachoma, an eye infection that can cause blindness. Over 300,000 people in Ethiopia are taking part. The goal is to see if this intensive approach works better than the current yearly trea…

This study is testing a new rapid blood test for syphilis that gives results from a fingerstick sample during a single clinic visit. About 600 adults attending a community health centre in Winnipeg will take part. Researchers want to see if this quick test is as accurate as stand…

This study tests whether taking doxycycline before potential exposure to STIs works better than taking it after exposure. 300 men who have sex with men will be randomly assigned to one of two groups and followed for 2 years. The goal is to see which approach better prevents chlam…

This Phase 3 trial tests whether a meningitis B vaccine (Bexsero) can prevent gonorrhea infections in men who have sex with men. 150 participants in Hong Kong will receive either the vaccine or a placebo. Researchers will compare infection rates and monitor safety.

This study follows 100 adults hospitalized in intensive care units with severe pneumonia caused by Mycoplasma or Chlamydia bacteria. Researchers will track how patients are treated, how long they stay in the hospital, and how many survive. They will also check for antibiotic resi…

This study examines how the COVID-19 pandemic affected syphilis cases and their interaction with HIV. Researchers will review medical records of 240 adults diagnosed with syphilis in Italy between 2017 and 2025. The goal is to see if pandemic restrictions led to delayed diagnoses…