Azoospermia

This study aimed to see if the drug clomiphene citrate could help men with a condition called non-obstructive azoospermia, where the body produces little to no sperm. The plan was to give the drug or a placebo for nine months, then check if sperm could be found in the semen or th…

This study tests two treatments—isotretinoin (an acne medication) and hCG (a hormone)—to see if they can help men with low or no sperm count produce moving sperm. About 100 men aged 19 to 50 will take one of the drugs for three months. The goal is to find new options for male inf…

This early study tests whether two drugs—denosumab and letrozole—can help men with a specific type of infertility (non-obstructive azoospermia) start producing sperm. Sixteen men will take the drugs for about three months, and researchers will check for sperm in their semen or te…

This experimental study tests whether frozen-thawed testis tissue, when grafted under the skin, can produce sperm in men with infertility. Five men will receive their own stored tissue. The goal is to see if viable sperm can be retrieved, potentially offering a future fertility o…

This study tests a non-surgical method to collect sperm from men with a condition called azoospermia, where no sperm is found in the semen. Using ultrasound guidance, doctors flush and suction fluid from a part of the testicle to retrieve sperm. If successful, this could help inf…

This study reviews medical records from about 400 couples where the male partner has a condition called non-obstructive azoospermia (NOA), meaning no sperm is found in the semen. All couples used IVF with a special sperm injection technique. The goal is to see if testing embryos …