Atrial septal defect 7
MONDO:0007173Atrial septal defect (ASD) with atrioventricular conduction defects is an extremely rare genetic congenital heart disease characterized by the presence of ASD, mostly of the ostium secundum type, associated with conduction anomalies like atrioventricular block, atrial fibrillation or right bundle branch block.
Also known as: ASD with or without atrioventricular conduction defects, NKX2-5 atrial heart septal defect, atrial heart septal defect caused by mutation in NKX2-5, atrial heart septal defect type 7, atrial septal defect-atrioventricular conduction defects syndrome, ASD7, atrial septal defect 7 with or without atrioventricular conduction defects
73 clinical trials for this condition and its sub-types, 0 tagged with Atrial septal defect 7 itself.
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A second chance for the thymus: could reimplanting it during heart surgery shield immunity?
Disease control Not yet recruitingThis pilot study tests whether putting back a child's own thymus tissue during heart surgery is safe and helps support the immune system. In some congenital heart disease surgeries, the thymus is removed to reach the heart, which may weaken immunity. Researchers will compare chil…
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Can a blood filter tame the inflammatory storm after pediatric heart surgery?
Disease control Not yet recruitingThis trial tests whether adding a blood-filtering device, called hemoadsorption, to the heart-lung machine can reduce harmful inflammation in children undergoing complex open-heart surgery. The device is designed to remove inflammatory proteins, known as cytokines, from the blood…
Sponsor: Norfaniza Zabidi • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Pre-surgery exercise program aims to boost heart fitness in adults born with heart defects
Disease control Not yet recruitingThis trial tests whether a personalized exercise program before heart surgery can improve physical fitness in adults with congenital heart disease. Participants are randomly assigned to either usual care or a 6-week prehabilitation plan with aerobic, breathing, and strength exerc…
Sponsor: Liverpool Heart and Chest Hospital NHS Foundation Trust • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Can a scan before birth predict a Baby's heart defect?
Diagnosis Not yet recruitingResearchers at Assiut University Hospitals are studying how well fetal heart scans before birth match the heart diagnoses babies receive after delivery. The study includes pregnant women referred for fetal echocardiography and newborns with confirmed critical congenital heart dis…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Sep 18, 2026 00:00 UTC
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Could a forehead sensor replace needle sticks for hemoglobin checks in kids?
Diagnosis Not yet recruitingThis study enrolls children and young adults scheduled for heart surgery or catheterization under general anesthesia. Researchers place a forehead sensor that measures tissue oxygen levels and use an algorithm to estimate blood hemoglobin. The goal is to see if this noninvasive m…
Sponsor: Boston Children's Hospital • Aim: Diagnosis
Last updated Jul 29, 2026 00:00 UTC
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Chest X-Ray may speed up heart defect detection in newborns
Diagnosis Not yet recruitingThis study will check how accurate chest X-rays are at finding congenital heart disease in newborns. Researchers will study 60 babies in the NICU who show signs of heart problems. Each baby gets a chest X-ray within 24 hours and an echocardiogram within 72 hours. By comparing the…
Sponsor: Assiut University • Aim: Diagnosis
Last updated Jun 27, 2026 12:05 UTC
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A window into the heart: new monitor may track oxygen in real time during pediatric surgery
Knowledge-focused Not yet recruitingThis observational study tests whether a new device, the SpectroCor Tissue Oxygenation Monitor, can accurately track oxygen levels in the heart muscle of children undergoing open-heart surgery. The device uses a sensor placed on the heart to measure oxygen availability during key…
Sponsor: Spectrocor • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC
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New device may help surgeons see blood flow during Kids' heart surgery
Knowledge-focused Not yet recruitingThis study will test a handheld device called IntraOx that uses light to measure oxygen levels in heart and liver tissue during complex heart surgery in children. The goal is to see if it can give surgeons useful information about blood flow without interfering with the operation…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Tiny probe tracks antibiotic in Kids' chests after heart surgery
Knowledge-focused Not yet recruitingThis study looks at how the antibiotic cefazolin spreads in the chest tissue of 10 children after heart surgery for congenital heart disease. A small probe placed during surgery will measure drug levels over 36 hours. The goal is to create a computer model to help doctors give th…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New ultrasound technique could reveal hidden brain risks in babies with heart disease
Knowledge-focused Not yet recruitingThis study will test a new, non-invasive ultrasound technique that captures brain blood flow in real time for infants with congenital heart disease. Researchers aim to understand how medical treatments and surgeries affect the brain, potentially explaining why some children later…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC